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Prof. Ofoefule Sabinus IFEANYI.

Department: Pharmceutical Technology And Industrial Pharmacy
Faculty: Pharmaceutical Sciences
Designation : Administrative Assistant
Email: sabinus.ofoefule@unn.edu.ng
Phone: +2348037905578


Publications (Articles and Journals):

1. Ofoefule S.I. and Chukwu, A: The Binding Properties of Treculia Africana Gum in Sodium Salycylate Tablets STP Pharm. Sci. 4 (6) 394-398 (1994), France.

2. Ofoefule S.I. and Ezomo, E.O.: Treculia Africana Gum as a Suspending Agent in Zinc oxide Suspension Pharmakefiki, 8: 14-22 (1995) Greece 

3. Orisakwe O.E., Ofoefule S.I. Dioka, S.E., Ufearos, C.S., and Nwobodo, E.O.: Carbon Black (N200): Possible Role in Poison Management. Tokai Exp. Clin. Med. 20 (2): 267-270 (2006). Japan 

4. Orisakwe O.E. Ofoefule S.I.: Plasma-Saliva Concentration of Rifamipcin in Man After Oral Administration Toki Exp. Clin Med. 21 (1): 45-46 (1996) Japan 

5. Orisakwe, O.E. Afonne, O.J. Dioka, C.E. Ufearo, C.S. and Ofoefule S.I. Effect of Activated Charcoal on Rifampicin Absorption in Man. Toki Exp. Clin. Med. 21 (1) 51-54 (1996) Japan 

6. Orisakwe, O.E., Afonne, O.J., Dioka, C.E., Ufearo, C.S. and Ofoefule S.I: Some Pharmacological Properties of Synclesia Scarbrida J. Med. Res. 103:282-284 (1996) India 

7. Orisakwe, O.E., Afonne, O.J., Dioka, C.E., Ufearo, C.S. and Ofoefule S.I: Investigation into the Oestrogen-like activity of Synclesia Scarbrida, Fitoterapia Vol. Levi No. 50:469-471 (1996) Italy 

8. Orisakwe, O.E., Ofoefule S.I., Dioka, C.E.: A Mini Review of Poisoning in Nigeria, West Afr. J.  Pharmacy 10(2) 53-55 (1996) West Africa.

9. Ofoefule S.I: Effect of Polyethyleneglycol 4000 (PEG 4000) solution on the In-vitro release profile of Nifedipine from Polymer Matrices Bio. Pharm Bull. 209(5) 574-576 (1997), Japan 

10. Ebi, G.C. and Ofoefule, S.I: Investigation into Folkloric Antimicrobial Activities of Landolphia Owerrience- Phytotherapy Research, 11: 149-151 (1917), Britain.

11. Uzoho, C.A., Ofoefule S.I. and Ejezie, C.N.: Physico-Chemical Properties of Mangifera indica Seed Fat used as a Suppository Base, Nig. J. Nat. Prod and Med., 1 36-40 (1997) Nigeria. 

12. Chukwu A., Okorie, O. and Ofoefule S.I: Some Properties of Film obtained from the Polysaccharide; Deuterium microcarpium Nig. J. Nat. Prod And Med., 1:36-40 (1997) Nigeria

13. Chukwu, A., Ofoefule S.I., and Ugoeze, K. Studies on the Pharmaceutical application of Polysaccharide Derived from Treculia africana fruit: Application as Sustained Release Matrix for Theophylline Hydrate Tablets. Boll Chim. Farmaceutico., 136(8):239-244(1997) Italy 

14. Adikwu, M.O. Ofokansi, K.C. and Ofoefule S.I. Utility of Chloranilic acid in Spectrophotometric Assay of Promethazine Hydrochloride, Boll. Chim. Farmaceutico., 136(5):450(1997)Italy

15. Ofoefule S.I. Chukwu A, Okorie, V.C. and Ugwah, M.O. Use of Dika Fat in the formulation of Sustained Release Frusemide Encapsulated Granules, Boll. Chim. Farmaceutico., 136(10):646-650 (1997) Italy

16. Ofoefule S.I and Esimone O; Studies on the Tableting Properties of Tacca involucrata Starch, Evaluation as a binder, Boll. Chim. Farmaceutic., 239-244 (1).(1998) Italy 

17. Ofoefule S.I. Studies on Tacca Involucrata Starch, Boll. Chim. Farmaceutico., 137(6) 218-22(1998) Italy

18. Ofoefule S.I. Chukwu., A. Nwankwo, C. and Orisakwe O.E: In-Vitro Properties of Ciprofloxacin Suppositories Formulated with Glycerogelatin and Theobroma Oil Bases, Boll. Chim. Farmaceutico., 137(9)341-344(1998) Italy   

19. Ofoefule S.I., Orisakwe O.E, Ibezim E.C., and Esimone C.O: Mechanism of Nifedipine Release from Tablets formulated with some Polymeric Materials, Boll. Chim. Farmaceutico., 137 (6):223-227(1998) Italy 

20. Ofoefule S.I. Uzuegbunam, C. and Attamah A.A: Effect of Some Direct Compression Excipients on the Stability of Pyridoxine Hydrochloride tablets Boll. Chim. Farmaceutico., 137(9):377-382(1998) Italy 

21. Ofoefule S.I and Amanambu C. Comparative Sustained Release Matrix Capacities of Some Polymer Matrices in Theophylline Hydrate Tables., J. Uni. Sci. Tech 18(2):47-50(1998) Ghana 

22. Ibezim, E.C. Ofoefule S.I. Ejeahalaka, C.N. and Orisakwe, O.E: In Vitro Adsorption of Ciprofloxacin on Activated Charcoal and Talc., Amer. J. Therap 6(4)199-201(1999), America 

23. Ofoefule S.I. and Chukwu, A.: Application of Microcrystalline Cellulose-Cissus Gum Combinations in the formulation of Aqueous Suspension. Boll Chim. Farmaceutico., 138 (5) 217-222 (1999) Italy.

24. Ofoefule S.I. and Okonta M. Adsorption of Ciprofloxacin: Evaluation of Magnesium Trisilicate, Kaolin and Starch as Antidotes for the Management of Ciprofloxacin Poisoning, Boll. Chim. Farmaceutico., 128(6)241-244 (1999) Italy

25. Ofoefule S.I., Chukwuobe, V.O. and Attamah, A.A. Effect of Direct Compression Excipients on the Stability of Ascorbic Acid Tablets Boll. Chim. Farmaceutico., 138: 418-421(1999) Italy 

26. Ofoefule S.I., Chukwu, A. Chima, E.I. and Ebi, G.C: Spectrophotometric Determination of Chlorpheniramine in some Dosage Forms using the Charge-transfer Complexation Technique. Analytical Letters., 32(15)2989-2997(1999) Ireland 

27. Ofoefule S.I. and Muko, K.N., Development of quick and simple method of Drug Identification and Assay in less equipped Quality Control laboratory: Qualitative and Quantitative detection of Chlorpheniramine on TLC plates using the Charge transfer Complexation Technique. Industrial Chemistry Research Communication., 1(1): 47-50 (1999) Nigeria 

28. Ofoefule S.I. and Chukwu, A.: Use of Acrylic and Methacrylic Acid Derivatives as Sustained Release Matrix for Theophylline Hydrate Tablets, Boll. Chim. Farmaceutico., 138 (10): 453-457, (1999) Italy 

29. Okafor, I.S, Udeala O.K., and Ofoefule S.I.: Comparative Study on Modified Starches in Direct Compression of a Highly Water to Soluble Drug; Chloroquine Sulphate. Boll. Chim. Farmaceutico., 139 (6) 252-255 (2000) Italy

30. Okafor I.S. Udeala O.K and Ofoefule S.I: Comparative Study on Modified Starches in Direct compression of a Poorly Water Soluble Drug; Hydrochlorothiazide. Boll. Chim. Farmaceutico., 140 (1): 36-39 (2000) Italy 

31. Ibezim, E.C. Attamah A.A., Dimgba, I.C., and Ofoefule S.I. Use of Carbopols- Sodium Carboxymethylcellose Admixture in the formulation of Bioadhesive Methronidazole Tablets: Acta. Pharm., 50 (2) 121-130(2000). Croatia

32. Ofoefule, S.I. Chukwu A. and Okoli. S.A. Mechanism behind Sustained Release Tablets prepared with Poly (Acrylic) Acid Polymers, Acta. Pharm., 50 (3 299-238 (2000) Croatia.

33. Ofoefule S.I. Chukwu, A; Use of Primogel on the release of frusemide from encapsulated granules, Acta. Pharm. 50 (2) 157-162 (2000), Croatia. 

34. Ofoefule S.I. and Ajali U. Spectrophotometric and some Thermodynamic Parameters of the Charge–transfer Complexation between Chloranilic Acid and Chlorpheniramine. Boll. Chim. Farmaceutico., 140 (5):364 (2000) Italy

35. Ebi G.C. and Ofoefule S.I: Antimicrobial Activity of Pterocarpus osun Stems. Fitoterapia 71:433-435 (2000) Italy.

36. Ilondu, N.D.A, Orisakwe, O.E., Ofoefule S.I. Afonne, O.J., Obi, E. Chilaka, K.C. and Orish, C.N. Pharmacokinetics of Diethylcarbamazine: Prediction by Concentration in Saliva. Bio. Pharm. Bull. 23 (4) 413-445 (2000) Japan 

37. Orisakwe, O.E., Ofoefule S.I., Ilondu N.D.A Afonne O.J. Obi, E. Chilaka, K.C. and Orish, C.N. Acceleration of Body Clearance of Diethylcarbamizine by Oral Activated Charcoal. Pharmacol Res. Vol. 0 No 01-4 (2000) Japan 

38. Ofoefule S.I., Onyeagba, O and Orisakwe, O.E.: Effect of Pefloxacin on Urinary and Salivary Concentrations of Isoniazide (INH) in Six Healthy Female Volunteers. Amer. J. Therap. 7 (5) 313-316 (2000) America 

39. Ofoefule S.I., and Chukwu A. Effect of some Hydrophilic Polymers on the In vitro Release Profile of Encapsulated Frusemide Granules Embedded in Lubritab. Nig. J. Pharm. 32:45-48( 2001) Nigeria 

40. Ofoefule S.I. Onuoha L.C., Orisakwe O.E. Okonta M. and Udeogaranya, O. Effects of Activated charcoal on Isoniazide Absorption in Rabbits. Boll. Chim. Farmeceutico., 140 (3), 183-186 (2001) Italy 

41. Ofoefule S.I., Okonta M and Udeogaranya O: Prediction of In vivo Bioavailability of Six Brands of Ciprofloxacin Film Coated Tablets using the concepts of Dissolution Efficiency. Boll. Chim. Farmeceutico., Vol. 140 (3) 187-191 (2001) Italy. 

42. Ofoefule, S. I., Chukwu, A; Anyakoha, N and Ebebe I. M: Application of Abelmoschus Esculentus in Solid Dosage formulation: 1; Use as Binder for Poorly Water- Soluble Drug. Indian J Pharm. Sci 63 (3): 216-220 (2001) India. 

43. Ofoefule, S. I. and Chukwu, A. Effects of Polyethylene Glycol 4000 (PEG 4000) and Sodium Lauryl Sulphate (SLS) on the Release of Hydrochlorothiazide (HCTZ) Embedded in Dika fat Matrix. Acta Pharm. (8) 233-239 (2001) Croatia 

44. Orisakwe, O.E Ilondu, N.D.A, Ofoefule, S.I., Afonne, O.J, Orish C.N and Agbassi, P.U: Effect of Activated Charcoal on Diethylcarbamazine Adsorption in Man. American J. Therap. 8 (1):7-10 (2001) America. 

45. Ofoefule, S.I: In Vitro Evaluation of the Bioadhesive Properties of Tacca Starch- Carbopol 940 Admixtures and their Application as Bioadhesive Systems for Metronidazole Tablets. J of Univ. Sci Tech.  21: 57-61 (2001) Ghana. 

46. Ofoefule S.I, Orisakwe O.E, Ilondu, N.A, Afonne, O.J, Maduka, S.O Anusiem C.A and Agbasi P.U: Some Plasma Pharmacokinetic Parameters Of INH In The Presence Of A Fluoroquinolone Antibacterial Agent. Amer. J. Therap 8 (4): 243-246 (2001) America.

47. Orisakwe, O.E. Agbasi P.U Affone O.J, Ofoefule, S.I., Obi E. and Orish, C.N, Rifampicin  Pharmacokinetics with or without Ciprofloxacin. Amer. J. Therap. 8, 151-153 (2001) America. 

48. Orisakwe O.E, Afonne O.J. Ofoefule, S.I and Obi, E: Adsorptive Capacity Of Activated Charcoal For Rifampicin with and without Sodium Chloride and Sodium Citrate. Bio.Pharm. Bull. 24 (6): 724-726. (2001) Japan. 

49. Agbasi P.U. Orisakwe O.E, Obi E., Ofoefule S.I., Ilondu N.A and Afonne, O.J.: Effect of Sulphate Cathartics on Adsorption of Rifampicin to Activated Charcoal. Indian J.Pharm. Sci. 320-322(2001) India.

50. Ofoefule S.I and Ike-Unor U: .In Vitro Evaluation of Bioadhesive Polymer / Tablet Delivery System For The Administration of Dequialinum Chloride to the Vaginal Epithelium. J. Phytomed. Therap. 6 (2) 96-107, (2001) Nigeria.

51. Orisakwe O.E, Oluboyo, A. Ofoefule, S.I. Obi, E. Ilondu, N, Afonne O.J. Agbasi P and Chioma D.H. Adsorption Studies of Artesunate: Evaluation of Saline Cathartics as Additive in The Management of Poisoning. J. Health Sc. 47 (5)1-4 (2001) Japan. 

52. Ofoefule S.I. Chukwu A and Ijezie P.P.: Prediction Of Relative In-Vivo Bio-Availability Of Pefloxacin Film Coated Tablets Based on Dissolution Efficiency Parameters. Nig. J. Pharmacy 32:39-41 (2001) Nigeria. 

53. Ofoefule S.I. and Chukwu A. Application of Abelmoschus Escculentus gum as a mini- matrix for Furosemide and Diclofenac Sodium Tablets. Indian J. Pharm. Sci. , 63 (6): 532-535 (2002) India. 

54. Esimone C.O. Ibezim E.C, Adikwu M.U., Ofoefule S.I, Nwafor S.V. and Onuoha O. Potential Application of Garcina Kola Seed as a Natural Antidote in the Management of Ciprofloxacin Poisoning: An In Vitro Study. Acta Pharm. 52: 219-226 (2002) Croatia 

55. Afonne O.J, Orisakwe O.E. Ofoefule S.I., Tsalha, S. Obi E, Ilondu N.A and Okorie O. Saline Cathartics and Adsorptive Capacity of Activated Charcoal for Doxycyline. Acta. Pol,. Pharm., 59 (3)177-179 (2002) Poland. 

56. Ofoefule S.I., Obodo, C.E., Orisakwe O.E. Afonne O.J, Ilondu N.A. Agbasi. O.U. Anusiem, C.A. Maduka S.O and Ilo C.E.: Salivary, Urinary and Plasma-Saliva Concentration Ratio of INH in the presence of Co-administered Ciprofloxacin. Amer. J. Therap. 91(1): 15-18 (2002) America.

57. Ibezim E.C. Esimone C.O., Ofoefule S.I and Chah, K.F.: Evaluation of the Microbiological Purity of some Syrups and Suspensions marketed in Nigeria. J. Phytomed Therap. 7(1&2):18:25-32 (2003) Nigeria. 

58. Ofoefule S.I.: In-Vitro Evaluation and Application of Carbopol 940 – Tragacanth Binary Mixtures in the Formulation of Bio-adhesive Hyoscine Hydrobromide Tablets. J. Phytomed Therap. 8: 25-32 (2003) Nigeria.

59. Ofoefule S.I. Ibezim E.C. Esimone O.C. Pepple, M.N Njoku C.J and Orisakwe O.E: Bioavailability of Metronidazole in Rabbits after Administration of a Rectal Suppository. Amer. J. Therap. 11 (3): 190-193 (2004) America. 

60. Orisakwe O.E. Agbasi P.U. Ofoefule S.I. Ilondu N.A. Afonne O.J. Anusiem C.A. Ilo, C.E. and Maduka S.O. Effect of Pefloxacin on the Urinary Excretion of Rifampicin. Amer. J. Therap. 10 (1): 13-16 (2004) America.

61. Orisakwe O.E Afonne O.J. Agbasi P.U and Ofoefule S.I. Urinary Excretion of Rifampicin in the presence of Ciprofloxacin. Amer. J. Therap. 11 (3): 171-174 (2004) America

62. Ofoefule S.I. Osuji A.C. and Okorie O: Effects of Physical and Chemical Modifications on the Disintegrant and Dissolution Properties of Tacca involucrata Starch. Bio-Research J. 2: 97-102 (2004). Nigeria 

63. Ohwoavworhua F.O Kunle O.O. and Ofoefule S.I. Extraction and Characterization of Microcrystalline Cellulose derived from Luffa Cylindrica plant. Afr. J. Pharm. Res. Dev. 1 (1): 1-6 (2004) Nigeria

64. Ofoefule S.I. Ibezim E.C. and Orisakwe O.E. Comparative Study of the In Vitro Adsorption of Some Drugs on Activated Charcoal. Afr. J. Pharm. Res. Dev., 1 (1):27-31(2004) Nigeria.

65. Ofoefule S.I. Use of Mathematical approximation in the elucidation of drug release mechanisms from high viscosity grade carboxymethylcellulose, J. Phytomed. Therap. 9:1-6 (2004) Nigeria

66. Emeje M.O. Kunle O.O and Ofoefule S.I.: Effects of Molecular Size of Carboxymethylcellulose on the Rate of Hydration, Matrix Erosion and Drug Release from its Matrix. Drug. Deliv. Tech. 5(3): 86-91 (2005) America.

67. Ofoefule S.I., Akpuba U and Emeje M.O.: Evaluation Of Tacca Leontopetalides Starch (Tacca Starch) as a Granulating Agent for Chloroquine Phosphate Tablets. J. Pharm. Res. 4 (1): 4-10 (2005) Nigeria. 

68. Ibezim E.C., Ofoefule, S.I., Evaluation of Colocynthis Vulgaris (Melon) seed cake as Binder for Tablet Formulations. Afr. J.Pharm.Res.Dev. 2(2): (2006) Nigeria.

69. Ohwoavworhua F.O and Ofoefule S. I. Evaluation of Disintegrant Properties of Microcrystalline Cellulose obtained from Luffa Cylindrica. Afr. J. Pharm. Res. Dev. 2 (1): 54-59 (2006) Nigeria

70. Ibezim E.C. and Ofoefule S.I. In Vitro Evalutaiton of the Bioadhesive Properties of Sodium Carboxymethylcellulose, Acacia, Veegum and their Admixtures. Afr. J. Pharm. Res. Dev. 2(1):67-72 (2006) Nigeria 

71. Emeje M.O. Kunle O.O and Ofoefule S.I. Effect of Molecular Size of Sodium Carboxymethylcellulose and Some Polymers on the Sustained Release of Theophylline from a Hydrophilic Matrix. Acta. Pharm., 56: 325-333 (2006) Croatia       

72. Ike-Uno U, Ofoefule S.I. and Chukwu A.: Evaluation of Gellan Gum as a Potential Pharmaceutical Adjuvant: Binding Properties in Tablets containing Poorly Water Soluble or Poorly Compressible Drug. Drug Delivery Science and Tech. 16 (5): 397-387 (2006) France.

73. Emeje M.O., Kunle O.O and Ofoefule S.I. Compaction Characteristics of Ethylcellulsoe in the Presence of some Channeling Agents. AAPS Pharm. Sc. Tech., 7(3): E1 E4 (2006) America. 

74. Emeje M.O., Kunle O.O and Ofoefule S.I.: Effects of the Molecular Size of Sodium Carboxymethylcellulose and pH on the Release of a Highly Water Soluble Drug, Chlorpheniramine maleate from Capsule Formulations. J. Phytomed. Therap. 11:23-30 (2006) Nigeria. 

75. Emeje M.O. Isimi C.Y Kunle O.O and Ofoefule S.I.: Effects of Polyethylene Glycol and Sodium Laurysulphate on the Compaction Characteristics of Eudragit. J. Applied Sciences. 7(8):2598-2603, (2007) ANSI.

76. Brown S.A. and Ofoefule S. I.: Effect of Molecular Size and Viscosity on the In vitro Bioadhesive Properties of Carboxymethylcellulose. Afr. J. Pharm. Res. Dev. Vol. 2 (2). (2006) Nigeria 

77. Ohwoavworhua F.O and Ofoefule S. I.:  Direct Compression Studies on Microcrystalline Cellulose derived from Luffa cylindrical Plant. Afr. J. Pharm. Res. Dev. 2 (2) 2006.Nigeria.

78. Franklin-Ude P.U, Emeje M.O. and Ofoefule S.I. Effect of Gellan gum as a mini-matrix for sustained release of Ephedrine Hydrochloride Granules. J. of Pharmacology and Toxicology. 2 (7): 646-652 (2007) ANSI.

79. Emeje M.O Elimimian, M, Isimi Y, Ike-Unor U, Kunle O.O and Ofoefule S.I.: Influence of some Common Filler-Binders on Product Properties for a Hydrophilic Matrix Sustained Release Tablets and Capsules. The Open Drug Deliv. J. 1:1-6 (2007) America.

80. Obonga W.O., Osadebe P.O, Esimone C.O., Ofoefule S.I and Onunkwo G.C.: Pharmacokinetics of Capsule Formulation of Crude Cannabis Resin in Rats. J. Bio-Resources 5 (1) 25 - 29 (2007) Nigeria.

81. Franklin-Ude P.U, Emeje M.O. and Ofoefule S.I: Evaluation of Gellan Gum as a Granulating Agent for Chloroquine Phosphate Tablets. J. Pharmacology and Toxicology, 3 (2): 53-63 (2008) ANSI.

82. Emeje, M.O., Elimimian, M., Isimi, C.Y., Ike-unor,U.,Kunle, O. and Ofoefule, S.I. Influence of some filler-binders on the sustained release properties of a hydrophilic matrix. J.Pharm.Res. 7(1): 44-48. (2008) India.

83. Emeje M.O. Nwabunike P.I., Isimi C.Y, Kunle O.O and Ofoefule S.I.: Hydro-Alcoholic media: an emerging in vitro tool for predicting dose dumping from controlled release matrices. J. Pharmacology and Toxicology, 3 (2): 84-92 (2008) ANSI.

84. Ibezim E.C., Ofoefule S.I., Omeje E.O, Onyishi V.I and Odo U.E.: The role of Ginger Starch as a Binder in Acetaminophen Tablets. Scientific Research & Essay. 3 (2): 046 – 050 (2008) Mauritius.

85. Ibezim E.C., Ofoefule S.I., Omeje E.O and Odo U.E.: Performance of Starch obtained from Dioscorea dumetorium as Disintegrant in Sodium Salicylate Tablets. Afr. Jour. Pharmacol. 2 (3): 052 – 058 (2008) Nigeria.

86. Emeje M., Nwabunike P., Isimi C., Fortunak J., Mitchell J.M., Byrn S. Kunle O. and Ofoefule S.I. Isolation, Characterization and Formulation Properties of a New Plant Gum Obtained from Cissus refescence. Int. J. Green Pharmacy. 3 (1): 16 – 23 (2009) India.

87. Ofoefule S.I., Eni-Ike N.E. Brown S.A. and Emeje M.O. In-vitro Release of Hydrochlorothiazide (HCTZ) from Gellan Beads. Asian J. Pharmaceutics. 3(2): 153-155. (2009) India. 

88. Emeje M. and Ofoefule S.I. Low level Maize Starch and Sodium Lauryl Sulphate as Release Modifiers in Carbopol 941 Capsule Matrix. Int. J. Green Pharmacy. 191-194. (2009) America.

89. Emeje, M.O., Eni-Ike, N.E., Brown, S.A. and Ofoefule, S.I. Preparation and in vitro release of hydrochlorothiazide from Gellan Beads produced by Ionotropic Gelation, Asian J. Pharmaceutics. 3(2): 153-155 (2009) India.

90. Emeje, M., Ihim ekpen, O., Isimi, C., Ofoefule, S.I. and Kunle, O. Isolation, Characterization and Compaction Properties of Alzelia africana Gum Exudates in Hydrochlorothiazide Tablet Formulations. Afr J. Pharm.Pharmacol. 3(5): 265-272 (2009) Nigeria.

91. Emeje M.O. Nwabunike P.I., Isimi C.Y, Kunle O.O and Ofoefule S.I. Preparation and evaluation of colon targeted drug delivery systems for albendazole using kneading extrusion and compaction technology, Acta Pharmaceutica Sinica. 44(10): 1-6 (2009) Turkey.

92. Ogbonna, J., Emeje, M. and Ofoefule, S. I. Effect of Low Level Sodium Lauryl Sulphate on the Sustained Release Polymer- based Matrix Tablets of Ciprofloxacin. Invent Rapid, Pharm. Tech, 1(1): 1-4, (2010) America.

93. Emeje, M. O., Franklin-Ude, P.I. and Ofoefule, S.I.; Evaluation of the Fluid Uptake Kinetics and Drug Release from Gellan Gum Tablets containing Metronidazole, Ind. J. Bio. Macromolecules XXX (2010) America.

94. Emeje, M.O., Ofoefule, S.I., Nnaji, A.C., Ofoefule, A.U. and Brown S.A. Assessment of bread safety in Nigeria: Quantitative Determination of Potassium Bromated and Lead. Afr. J. Food Sci. 4(6): 394-397, (2010) Kenya.

95. Emeje, M., Izuka, A, Isimi, C., Ofoefule, S.I. and Kunle, O. Preparation and Standardization of a Herbal Agent for the Therapeutic Management of Asthma; Pharm. Dev. Tech. 1-9, (2010) USA. 

96. Emeje, M.O., Kunle, O. and Ofoefule, S.I. et al; Oral sustained Release Tablets of Zidovudine using Binary Blends of Natural and Synthetic Polymers. Biol. Pharm.Bull. 33 (9): 1551-1557 (2010) Japan.

97. Mbah C.C., Ofoefule, S. I and Chukwu, A. Evaluation of some Starches as Disintegrants in Sodium Salicylate Tablet Formulations. Nig. J. Pharm.Research 3 (1): 203 – 217 (2010) Nigeria.

98. Emeje, M, Izuka A, Isimi, C, Ofoefule, S.I and Olabayo, K. Preparation and Standardization of a Herbal Agent for the Therapeutic Management of Asthma.  Pharm. Dev. Tech. 16 (2): 170 – 178 (2011) America.

99. Jackson, C and Ofoefule, S.I. Use of Xanthan gum and Ethylcellulose in formulation of Metronidazole for Colon Delivery. J. Chem. Pharm. Res. 3(2): 11 – 20 (2011) America.

100. Emeje, M., Boyi, S., Obidike, I., Isimi, C., Kunle, O and Ofoefule, S. Natural Antidiabetic Compound for the Therapeutic Management of Diabetic Mellitus and its Drug Delivery System. J. Dietary Supplements. 1 – 14 (2011) America.

101. Ogbonna, J., Emeje, M., Mumini, M, Attama, A and Ofoefule, S. The Dual Role of Carboxymethylated Starch in Monolithic polymeric matrices of Ciprofloxacin. Int. J. Pharm. Sci. 3: 419 – 423 (2011) India.

102. Emeje, M, Isimi, C, Fortunak, J, Mitchell, J, Byrn, S, Kunle, O and Ofoefule, S. Extraction and Physicochemical Characterization of a New Polysaccharide obtained from Fresh Fruits of Abelmoschus esculentus. Iranian J. Pharm. Sci. 10 (2): 237 – 246 (2011) Iran.

103. Emeje, M. O, Okolo, P. I., Isimi, C.Y and Ofoefule, S.I. Multilayered Tablets of vitamin A Palmitate using Blends of Vegetable Fat with Xanthan and Guar Gums. J. Pharm. Sci. Tech. 3(7): 631-644 (2011) India.

104. Onugha, O.N and Ofoefule, S. I. The place of Specialized Pharmaceutical Services in Hospital Pharmacy Practice. Nig. J. Pharm. Allied Sci. Res. 1(1): 66 – 73(2011) Nigeria.

105. Emeje, M, John Africa, L, Isimi, Y, Kunle, O and Ofoefule, S. Eudraginated polymer blends: A Potential Oral Controlled Drug Delivery System for Theophylline. Acta Pharm., 62: 71 – 82 (2012) Croatia. 

106. Umeh, O.N.C, Emeje, M. O, Ofoefule, S. I., Effect of some channeling agents on the release of DFK from Hydrophobic polymer matrix. Res. J. Pharm. Bio. Chem. Sci., 3(4): 1173 – 1177 (2012). India.  

107. Emeje, M. O, Kalita, R, Isimi, C, Buragohain, A, Kunle, O and Ofoefule, S. I., Synthesis, Physicochemical characterization and functional properties of an Esterified starch from under – utilized sources in Nigeria. Afr. J. Food. Agr. Nutri. Dev. 12 (7): 7001 – 7018 (2012) Kenya.

108. Umeh, O.N.C, Ezeagba, J. C and Ofoefule, S. I., Effect of Hydrophilic diluents on the release profile of Grisofulvin from Tablet formulations. Ind. J. Pharm. Sci. 75 (6): 726 – 729 (2013) India.

109. Umeh O.N.C, Orji I.E. and Ofoefule S.I. Effects of particle size and some formulation additives on the dissolution profile of Ibuprofen from compressed tablets. INDO American J. Pharm. Res. 4 (01):439-444 (2014)

110. Akpabio I.E. and Ofoefule S.I. Formulation and evaluation of ciprofloxacin hydrochloride vaginal pessaries. Nig. J. Pharm. Appl Sci. Res 3(2):43-50 (2014)

111. Igboasoiyi A.C, Attih E.E, Ofoefule S.I., Umoh E.D and Udoh O.C. Spectrophotometric determination of ciprofloxacin using charge-transfer complexation technique. Int. J. Innov. Res. Dev. 3(11):177-182 (2014)

112. Nwachukwu N, Emeje M.O. and Ofoefule S.I. Evaluation of poly(acrylic) acid polymers as a sustained release matrix for ciprofloxacin hydrochloride. Int. J. Sci. Tech. Soc. 2(4):85-90 (2014)

113. Nwachukwu N, Emeje M.O. and Ofoefule S.I. Formulation and in vitro evaluation of vitamin A palmitate tablets containing carbopol 971. Amer. J. Pharm. Pharmacol. 1(4):45-50 (2014) 

114. Nwachukwu N, Emeje M.O. and Ofoefule S.I. Application of carbopol 971 as a sustained release matrix for theophylline hydrate tablets. Amer. J. Pharm. Pharmacol. 1(4):6-11 (2014) 

115. Umeh O.N.C, Nworah A.C. and Ofoefule S.I. Physicochemical properties of microcrystalline cellulose derived from Indian bamboo (Bambusa vulgalis) Int. J. Pharm. Sci. Rev. Res; 29(2):5-9 (2014)

116. Jackson C, Emeje M.O and Ofoefule S.I. Ternary Blends of some Hydrophilic and Hydrophobic Polymers in Colon Targeted Delivery of Metronidazole. International Journal of Drug Delivery; 6(3):305-310 (2014).

117. Jackson C, Emeje M.O and Ofoefule S.I. Use of Xanthan gum in the formulation of Diethylcarbamazine for targeted drug delivery. Bri J. Pharm. Res. 5(4):280-285 (2015). 

118. Jackson C, Emeje M.O and Ofoefule S.I. Statistical comparison of the release profiles of Diethylcarbamazine from guar gum and ethylcellulose matrices. Int. J. Res. Pharm. Bio. Sci. 2(3):25-29(2015). 

119. Ifiora B.I. Ezenyi C.I., Ofoefule S.I. and Emeje M.O. Assessment of bread safety in Nigeria: One decade after the ban on the use of potassium bromated. Food Proc. Technol 6(1):1000409 (2015).

120. Akapbio, E. I and Ofoefule, S.I. Formulation and Evaluation of Ciprofloxacin hydrochloride vaginal Tablet and Gel; Nig. J. Pharm. Allied Sci. Res. 4 (1): 25 – 33 (2015).

121. Umeh, O.N.C, Ekeugo, U.E and Ofoefule, S. I. Effect of Particle Size and Some Formulation Components on the Mechanical Properties and in vitro Release Profile of Metronidazole from Compressed Tablets. American J. Pharm. And Pharmacology 2(4):28-34(2015).

122. Ogbonna, J. I and Ofoefule, S. I., The Anti-diabetic effects of the Bioactive Flavonoid (Kaempferol – 3- 0-β-D-6 {P-Coumaroyl}) isolated from Allium cepa; Recent Patent on Anti-Infective Drug Discovery 11: 44-52 (2016). 

• Nwachukwu, N and Ofoefule, S. I. Effect of Drying Methods on the Powder and Compaction of Microcrystalline Cellulose derived from Cocos nucifera.J. Pharm. Res. Int. 20(2):1-15(2017).

II CONFERENCE PAPERS REFEREED AND PUBLISHED AS PROCEDINGS 

123. Chukwu A, and Ofoefule S.I.: Prolonged Release Hydrochlorothiazide from a new swellable polymer matrix. Proc. 18th Pharm. Tech. Conf. Exhibition, Utrecht. The Netherlands, 13-15 April 1999, Vol. 1, Pp. 214-234.

124. Ofoefule S.I. and Chukwu A., Spectrophotometric Assay of Amitriptyline Hydrochloride using Charge-Transfer Complexation Technique, Ibid, 1999, Vol. 1, pp 300-308.

125. Ofoefule S.I. and Chukwu A. In- vitro Evaluation of Poly (acrylic) acid polymer -Veegum Binary Mixtures as Bioadhesive System for Metronidazole Tablet. Proc. 19th Pharm. Tech. Conf. Baveno Stresa, Italy, April 11-13, 2000 Vol. 3, Pp 247-255

126. Ofoefule S.I and Chukwu A. Application of the Principle of Charge Transfer Complex Formation for the Spectrophotometric Assay of Cinnarizine in Solid Dosage Forms. Ibid, 2000, Pp 162-170

127. Ofoefule S.I and Chukwu A: Sustained Release Characteristics of Frusemide and Diclofenac Sodium from Mini Matrix of a Plant Hydrocolloid. Proc. 20th Pharm. Tech. Conf. Liver Pool UK, April 24-26, 2001.

128. Ofoefule S.I. Total Quantity Management in the Industry and Recent Advances in    Pharmaceutical Analysis. Proc. Mandatory Continuing Pharmacy Education, Vol. 1. 2001. 

129. Ofoefule S.I. Application of Packaging Material in Pharmacy, Proc. Mandatory Continuing Pharmacy Education, Vol. 2; 2002, Pp 1-10.

130. Anyakoha N and Ofoefule S.I. The Impact of Differential Remuneration on the Strength and Quality of Healthcare Delivery in a Depressed Economy. Poster Presentation at the Health Research and Education Trust (HRET) Conference, Geneva, Switzerland. March 22-23,  2007

131. Emeje M.O, Ofoefule S.I. and Kunle OO. Effect of Polyethylene glycol and sodium lauryl sulphate on the compaction characteristics of Eudragit and drug release from its matrix, PSWC 2007, Amsterdam, The Netherlands.

132. Nwabunike P, Emeje M, Isimi Y, Kunle O.O. and Ofoefule S. Formulation and evaluation of colon targeted drug delivery systems for albendazole. Drug Discovery and Delivery Conference, Dubai, 2008

133. Emeje M, Obidike I, George A and Ofoefule S. Anti tubercular efficacy of rifampicin-loaded starch nanoparticles. Keystone symposium on Molecular and Cellular Biology: E.I., Drug resistance and persistence in tuberculosis, Kampala, Uganda, 2012.

134. Ofoefule S.I. Health Promotion and Education (Deworming, lifestyle modification, smoking cessation, exercise and weight management, Proceedings of PCN MCPD programme for the Recertification of Pharmacists in Nigeria, 2013, pp. 137-146

135. Ofoefule S.I. and Momoh M.A. Regulatory issues in Pharmacy in Nigeria, proceedings of PCN MCPD program for the Recertification of Pharmacists in Nigeria, 2014

136. Umeh, O.N.C, Ezeagwu, K.C and Ofoefule S.I. Micromeritic, granulating and dissolution properties of rice starch in metronidazole based formulations. 7th International Granulation Conference, Sheffield, United Kingdom, 1-3 July, 2015.

137. Okorie, J.E, Ubah F.N, Umeh O.N.C and Ofoefule S.I. Formulation and evaluation of methacrylic and Polyacrylic acid matrix tablets of mebendazole for colon targeted drug delivery. 7th International Granulation Conference, Sheffield, United Kingdom, 1-3 July, 2015.

 

a) BOOKS

138. Ofoefule S.I (2001), Genuine and Counterfeit Drug Detection Techniques Vol. 1. Mike Soc. Press, Nsukka, Nigeria 

139. Ofoefule S.I. (2002). Editor, A Textbook of Pharmaceutical Technology and Industrial Pharmacy. Samakin Nigeria. Ent. Lagos, Nigeria.

140. Onyechi J.O., Chukwu, A., Ofoefule, S. I., Onunkwo, G.C et al., (2008). Introductory Formulation Science Volumes I, II & III. Global Publishers, Nsukka.

b) TECHNICAL REPORT

141. Ofoefule S.I. A Survey of Commonly Prescribed Products which are very prone to faking in the Nigerian Drug Market, Submitted to Government of Enugu State of Nigeria, Health System Development Project II (World Bank Assisted).

C) CHAPTERS IN BOOKS 

142. Ofoefule S.I. Tablets Dosage Forms 1 in: A Textbook of Pharmaceutical Technology and Industrial Pharmacy, Samakin Nig. Ent. Lagos, Nigeria (2002)

143. Ofoefule S.I. Tablets Dosage Forms 11 in: A Textbook of Pharmaceutical Technology and Industrial Pharmacy, Samakin Nig. Ent. Lagos, Nigeria. (2002)

144. Ofoefule S.I. Tablets Dosage Forms 111 in: A Textbook of Pharmaceutical Technology             and Industrial Pharmacy, Samakin Nig. Ent. Lagos, Nigeria. (2002)

145. Ofoefule S.I and Okorie, O. Tablets Dosage Forms IV In: A Textbook Of Pharmaceutical Technology and Industrial Pharmacy, Samakin Nig. Ent. Lagos, Nigeria (2002)

146. Ofoefule S.I. and Chukwu A, Sustained Release Dosage Forms: Design and Evaluation of Oral Products In: A Textbook of Pharmaceutical Technology An Industrial Pharmacy, Samakin Nig. Ent. Lagos, Nigeria. (2002) 

147. Ofoefule S. I. Pharmaceutical Suspensions, Preparations, Properties and Evaluations In: A Textbook of Pharmaceutical Technology and Industrial Pharmacy, Samakin Nig. Ent. Lagos, Nigeria (2002)

148. Ofoefule S.I. Design, Manufacture and Quality Control of Perenteral Products In: A Textbook Of Pharmaceutical Technology and Industrial Pharmacy Samakin Nig. Ent. Lagos, Nigeria (2002)

149. Ofoefule S.I Effervescent Dosage Forms, Chewable Tablets and Medicated Lozenges In: A Textbook of Pharmaceutical Technology and Industrial Pharmacy, Samakin Nig. Ent. Lagos, Nigeria (2002)

150. Okorie, O and Ofoefule S.I Creams and Ointment In: A Textbook of Pharmaceutical Technology and Industrial Pharmacy, Samakin Nig. Ent. Lagos, Nigeria (2002).

151. Ofoefule S.I.  Relevant Industrial Laws In: A Textbook of Pharmaceutical Technology and Industrial Pharmacy, Samakin Nig. Ent. Lagos, Nigeria. (2002)

152. Ofoefule S.I. Relevant Pharmarcokinetics In: A Textbook of Pharmaceutical Technology and Industrial Pharmacy, Samakin Nig. Ent. Lagos, Nigeria. (2002)

153. Ofoefule, S.I., Attama, A. A, Biopolymer blends: Applications, limitations and future prospects. In: Biopolymers in drug delivery: Recent Advances and Challenges. Adikwu, M.U. and Esimone, C.O. (Eds.), Bentham Sciences Publishers, UAE, eISBN: 978-1-60805-078-9, pp. 198-223 (2009).

154. Emeje, M. O, Obidike, I. O, Akpabio, E. I and Ofoefule, S.I., Nanotechnology in drug delivery. In: Recent Advances in Novel Drug carrier systems. Ali Demir Sezer (Ed.) Open Access Publisher, Janeza Trdine 9, 51000 Rijeka, Croatia. Chapter 4, 69 – 105 (2012). ISBN 978953-51-0810-8  INTECH: http//www.intechopen.com/articles/show/title/nanotechnology-in-drug-delivery. 

 


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