A rho value of +0.21 is reported for the reaction of mono 4-substi- tuted benzophenones with formamide. This, in conjunction with a kinetic iso- tope effect value of 1.80 obtained for the system, suggests a rate-limiting C-H bond cleavage.
Tetrahedron 12/1990; 46(6):1899–1910. DOI:10.1016/S0040-4020(01)89758-1
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