REPRODUCTIVE AND DEVELOPMENTAL PROGRAMMING RESEARCH GROUP.
INTRODUCTION
It is beyond dispute that for each individual, the genetic endowment at conception sets the limits on the capacity for metabolic and reproductive function (Lau and Rogers, 2005). From a range of diverse fields including evolutionary ecology and molecular biology, however, it is now well established that the extent to which this capacity is achieved or constrained is determined by the environmental experience. The consequences of these experiences tend to be cumulative throughout life and express themselves phenotypically as achieved growth and body composition, hormonal status and the metabolic capacity for one or other function (Lau and Rogers, 2005).
At any time later in life, the response to an environmental challenge, such as stress, infection or excess body weight is determined by an interaction amongst these factors. When the metabolic capacity to cope is exceeded, the limitation in function is exposed and expresses itself as overt disease (Lau and Rogers, 2005). During early life and development the embryo, foetus and neonate are relatively plastic in terms of metabolic function (Lucas, 1991). The effect of any adverse environmental exposure is likely to be more marked than at later ages and the influence is more likely to exert a fundamental effect on the development of metabolic capacity. This has been characterized as “programming”-a process whereby a stimulus or stress at a critical period of development has lasting or lifelong significance (Lucas, 1991; Ross and Desai, 2005; Armitage et al., 2005).
Programming may result in altered cell number, organ structure, hormonal set points, and gene expression among others (Lau and Rogers, 2005). Although overt structural defects are usually associated with functional deficiency, the reverse is not necessarily true. Biochemical changes induced by prenatal and/or early postnatal insults that lead to physiological deficits of organ function may not always be accompanied by detectable anatomical abnormalities. Hence in recent decades, considerable attention has been drawn to functional teratology, an extension of the investigation beyond morphological examinations to include the evaluations of functional integrity of organ systems. Effects of programming may be permanent or expressed only at select offspring ages eg newborn, adult and may be dependent on the in utero environment eg nutrition, glucocorticoid or the early postnatal environment. Furthermore, expression of physiological abnormalities maybe present during basal conditions or restricted to environmental stress or disease states in the offspring (Lau and Rogers, 2005).
References
Armitage, J.A., Taylor, P.D., Poston, L. (2005). Experimental models of developmental programming: consequences of exposure to an energy rich diet during development
Journal of Physiology 15:565 (pt 1): 3-8
Lau, C. and Rogers, J.M. (2005). Embryonic and fetal programming of physiologic disorders in adulthood. Birth Defects Research (Part C) 72, 300-312.
Lucas, A. (1991). Programming by early nutrition in man. In Rock GR, Whelam J (eds): The childhood environment and adult disease (CIBA foundation symposium 156). Chichester:
Wiley 38-35
Ross, M.G. and Desai, M. (2005). Gestational programming: population survival effects of drought and famine during pregnancy. American Journal of Physiology Regulatory Integrative and Comparative Physiology 288: R25-33.
RESEARCH FOCUS:
To understand the mechanisms by which maternal perinatal nutritional perturbations program the development of the offspring phenotype with particular emphasis on the development and functioning of the reproductive system and the gut-brain nutrient sensing pathway.
OBJECTIVES
- To investigate how maternal perinatal nutritional perturbations affect placental development and function and how this relates to the offspring phenotype later in life (in the post-weaning period).
- To investigate the relationship particularly between the onset of puberty, mating behavior, pregnancy success rate, pregnancy outcomes and the development and functioning of the gut-brain nutrient sensing pathways in the offspring and maternal perinatal nutritional perturbations.
DESCRIPTION OF TEAM’S RESEARCH PLAN
The achievement of the research objectives will be based on the assessment of: 1) pregnancy and lactation outcomes in nutritionally perturbed dams and 2) offsprings’ postnatal growth, and the development and functioning of the reproductive system and the nutrient sensing pathways in the gut-brain axis.
The offsprings will at no time during their development be directly exposed to nutritional perturbations but will only be indirectly exposed through their mothers. These offsprings will be studied alongside their mothers in groups reflecting the periods during their development when they will be exposed to nutritional perturbations through their mothers. Postnatal growth and development will be assessed by measuring the weights and lengths of the offsprings, some growth promoting hormones as well as some internal organ weights and histologies at birth and then weekly until post-natal day 60. Onset of puberty will be assessed by determining the age in days at vaginal opening for the female offspring and balanopreputial separation for the male offspring. In adulthood, mating behaviours and reproductive success rates will also be assessed using established experimental reproductive techniques in rats. Development and functioning of the gut-brain nutrient sensing pathway will be investigated using established experimental protocols.
COMPOSITION OF GROUP
- Dr Eghosa E. IYARE (Coordinator)
Senior Lecturer,
Dept of Physiology,
College of Medicine, UNEC.
Phone: +2348052820041
- Dr Festus E. IYARE,
Associate Professor,
Dept of Pathology,
Ebonyi State University,
Abakaliki.
- Charles O. Ezeh,
Lecturer I,
Dept of Medical Biochemistry,
College of Medicine, UNEC.
- Mr Kenneth A. Okojie,
Ph.D Student,
Dept of Physiology,
College of Medicine, UNEC.
- Mr Maruf E. Balogun,
Ph.D Student,
Dept of Physiology,
College of Medicine, UNEC.
- Miss Cordilia U. Igberaese,
M.Sc. Student,
Dept of Physiology,
College of Medicine, UNEC.
BRIEF CVs OF MEMBERS
Name: IYARE, EGHOSA EDORISIAGBON
Place and Date of Birth: Benin City, 2nd March, 1974
Age: 41 years
Present Postal/Email Address: Department of Physiology, College of Medicine, University of Nigeria, Enugu Campus, Enugu. eghosa.iyare@unn.edu.ng; gimagosa@yahoo.com
GSM number: 08052820041
Nationality: Nigerian
Marital Status: Married
Name and Address of Spouse: Dr (Mrs) Iyare, Oluwatoyin Ibukun, Department of Pathology, Federal Teaching Hospital, Abakaliki, Ebonyi State.
Number Of Children With Ages: Four (12years, 8years, 5years, 3years)
Next of Kin: Dr (Mrs) Iyare, Oluwatoyin Ibukun
Institutions Attended With Qualifications Obtained And Dates:
- Edo College, Benin City: Senior Secondary School Certificate (SSSC), 1992
- University of Lagos, Lagos: B.Sc. Physiology, 1997
- University of Lagos, Lagos: M.Sc. Physiology, 2000
- University of Lagos, Lagos: Ph.D. Physiology, 2010
Previous Employments With Dates:
- Graduate Assistant, March 1999 – September, 2000
- Assistant Lecturer, October 2000 – September 2001
- Lecturer II, October 2001 – September 2004
- Lecturer I, October 2004 – September 2008
- Senior Lecturer, October 2008 – Date
Duties Performed:
- Graduate Assistant:
Coordinating and organizing Physiology practical for the students of the Faculties of Medical Sciences (2nd and 3rd year medical students), Dentistry (2nd and 3rd year dental students), Health Sciences and Technology (Medical laboratory sciences, Medical rehabilitation, Medical radiography and Nursing sciences).
- Assistant Lecturer:
Teaching and examining students of the Faculties of Medical Sciences (2nd and 3rd year medical students), Dentistry (2nd and 3rd year dental students), Health Sciences and Technology (Medical laboratory sciences, Medical rehabilitation, Medical radiography and Nursing sciences students) Gastrointestinal Physiology, Neurophysiology and Endocrine and Reproductive Physiology.
Coordinating and organizing Physiology practical for these groups of students.
- Lecturer II:
Same as for Assistant Lecturer
- Lecturer I:
Teaching and examining students of the Faculties of Medical Sciences (2nd and 3rd year medical students), Dentistry (2nd and 3rd year dental students), Health Sciences and Technology (Medical laboratory sciences, Medical rehabilitation, Medical radiography and Nursing sciences students) Gastrointestinal Physiology.
Organizing Physiology practical, in these areas, for these groups of students.
- Senior Lecturer:
Teaching and examining students of the Faculties of Medical Sciences (2nd and 3rd year medical students), Dentistry (2nd and 3rd year dental students), Health Sciences and Technology (Medical laboratory sciences, Medical rehabilitation, Medical radiography and Nursing sciences students) in Excitable Tissues.
Teaching and examining Postgraduate Physiology Students in Cell and Excitable Tissues, Gastrointestinal Physiology, Reproductive Physiology, Research Methodology and Laboratory Techniques in Physiology
Organizing Physiology practical, in these areas, for these groups of students.
Supervised Eight (8) M.Sc. Projects and one (1) Ph.D thesis and currently supervising four (4) M.Sc students and two (2) Ph.D students.
Other Duties Performed:
- Member, Disciplinary committee, Faculty of Medical Sciences, College of Medicine, University of Nigeria, Enugu Campus, Enugu. 2004-2010.
- Member, Examination committee, Department of Physiology, College of Medicine, University of Nigeria, Enugu Campus, Enugu. 2005-2010.
- Member, Postgraduate program committee, Department of Physiology, College of Medicine, University of Nigeria, Enugu Campus, Enugu. 2007-2010.
- Chairman, Examination committee, Department of Physiology, College of Medicine, University of Nigeria, Enugu Campus, Enugu. 2010-2011.
- Coordinator, Postgraduate program, Department of Physiology, College of Medicine, University of Nigeria, Enugu Campus, Enugu. 2010-2012.
- Acting Head, Department of Physiology, College of Medicine, University of Nigeria, Enugu Campus, Enugu. 01/08/ 2012-31/07/2013.
- Editor In Chief, Nigerian Journal of Experimental and Clinical Biosciences 2012-Date.
Attendance at Conferences
Conference Title Date Place
22nd Annual Scientific Conference of Physiological 2002 Ibadan
Society of Nigeria
23rd Annual Scientific Conference of Physiological 2003 Lagos
Society of Nigeria
25th Annual Scientific Conference of Physiological 2005 Benin
Society of Nigeria
26th Annual Scientific Conference of Physiological 2006 PH
Society of Nigeria
28th Annual Scientific Conference of Physiological 2008 Ilorin
Society of Nigeria
30th Annual Scientific Conference of Physiological 2010 Ikeja
Society of Nigeria
Workshop/Training Date Place
International Brain Research Organization July 18-26, 2007 University of Lagos
(IBRO) Neuroscience Course
Medical Education Partnership Initiative July 11-12, 2013 University of Ibadan
Nigeria (MEPIN) organized Training on
Computer assisted practical exercise in
Physiological Sciences
Medical Education Partnership Initiative July 30-31, 2013 University of Nigeria
Nigeria (MEPIN) Training of Trainers on
Teaching by Case Based Methods
Professional Review of Papers for Reputable Journals
Title of Papers Reviewed Journal Date
Chronic administration of aqueous Pharmaceutical 20/5/2011
Extract of Hibiscus sabdariffa alone Biology
and in combination with valsartan
attenuates hypertension in 2-kidney
1-clip Hypertensive rats: A comparative
study with valsartan.
Anticancer activity of flavonol and Pharmaceutical 3/7/2012
flavan-3-ols rich extract from Croton Biology
celtidifolius Baill latex
Exposure of pregnant rats to genistein Pharmaceutical 31/5/2014
alters amniotic fluid, placental, and Biology
plasma, leptin level; maternal thyroid
hormones, and c-reactive protein
Referees:
- Prof R.O NNELI,
Dept Of Physiology,
Faculty of Basic Medical Sciences,
Federal University, Ndufu-Alike, Ikwo,
Ebonyi State, Nigeria.
- Prof E. N. SHU,
Dept Of Pharmacology and Therapeutics,
College of Medicine, University of Nigeria,
Enugu Campus, Enugu,
Nigeria.
- Prof I. E. EZEAGU,
Dept Of Medical Biochemistry,
College of Medicine, University of Nigeria,
Enugu Campus, Enugu,
Nigeria.
Publications
Research Articles
- ADEGOKE, O. A. and IYARE, E. E. (1999): Metabolic Action Of Sex Steroids: The Effects Of Testosterone and Progestins On Hepatic Glycogen Deposition. Nigerian Quarterly Journal of Hospital Medicine 9 (1) 71-73.
- ADEGOKE, O. A.; IYARE, E. E. and Gbenebitse S. O. (2003): Fasting plasma glucose and cholesterol levels in pregnant Nigerian women. Nigeria Postgraduate Medical Journal. 10 (1): 32-36.
- IYARE, E. E. and IYARE, F. E. (2006): Lactational exposure to an aqueous extract of Hibiscus Sabdariffa (Hs) accelerates offspring’s early postnatal growth in Sprague-Dawley rats. Journal of Experimental and Clinical Anatomy. 5(1): 6-9.
- IYARE, E. E. and IYARE, F. E. (2006): Effect of in utero exposure to an aqueous extract of Hibiscus sabdariffa on offspring’s postnatal growth in Sprague-Dawley rats. Nigerian Journal of Health and Biomedical Sciences. 5 (1): 27-30.
- IYARE, E. E. and IYARE, F. E. (2006): The effect of an aqueous extract of Hibiscus sabdariffa on gestational weight gain, pregnancy outcome and postpartum weight retention in Sprague-Dawley (SD) rats. Nigerian Journal of Health and Biomedical Sciences. 5 (2): 26-29.
- IYARE, E. E. and IYARE, F. E. (2007): Maternal consumption of aqueous extract of Hibiscus sabdariffa during pregnancy attenuates pregnancy weight gain and postpartum weight loss. African Journal of Biomedical Research 10: 257-261.
- IYARE, E. E. and ADEGOKE, O. A. (2008): Mechanism of the delayed puberty onset in offspring of rats that consumed aqueous extract of hibiscus sabdariffa during pregnancy. Nigeria Journal of Physiological Sciences 23 (1-2): 71-77.
- IYARE, E. E. and ADEGOKE, O. A. (2008): Maternal consumption of an aqueous extract of Hibiscus sabdariffa during lactation accelerates postnatal weight and delays onset of puberty in female offspring. Nigeria Journal of Physiological Sciences 23 (1-2): 89-94.
- IYARE, E. E. and ADEGOKE, O. A. (2008): Body mass index at onset of puberty in rats exposed to aqueous extract of Hibiscus sabdariffa in utero. African Journal of Biomedical Research 11: 203-208.
- IYARE, E. E. and IYARE, F. E. (2008): Effect of prenatal and postnatal exposure to an aqueous extract of Hibiscus sabdariffa on postnatal growth in Sprague-Dawley rats. Pakistan Journal of Nutrition 7 (2): 255-257.
- IYARE, E. E. and ADEGOKE, O. A. (2008): Postnatal weight gain and onset of puberty in rats exposed to aqueous extract of Hibiscus sabdariffa in utero. Pakistan Journal of Nutrition 7 (1): 98-101.
- NWAGHA, U. I., EJEZIE, F. E. and IYARE, E. E. (2009): Evaluation of serum uric acid levels in normal pregnant Nigerian women. Nigerian Journal of Clinical Practice. 12 (1) 83-86.
- IYARE, E. E. and NWAGHA, U. I. (2009): Postweaning Consumption of Aqueous Extract of Hibiscus sabdariffa May Predispose Rats to Obesity. Pakistan Journal of Nutrition 8 (11): 1760-1765. Journal of Phytology 2010, 2(2): 01–09
- IYARE, F. E., IYARE, E. E. and ADEGOKE, O. A. (2009): Morphologic changes in the utero-ovarian tissues of the offspring of rats that consumed aqueous extract of Hibiscus sabdariffa calyx during lactation. Journal of Experimental and Clinical Anatomy 8 (2): 10-15.
- IYARE, E. E. and NWAGHA, U. I. (2009): Delayed puberty onset in rats that consumed aqueous extract of Hibiscus sabdariffa during the juvenile-pubertal period. Pakistan Journal of Biological Sciences 12 (23): 1505-1510.
- IYARE, E. E., ADEGOKE, O. A. and NWAGHA, U. I. (2010): Mechanism of delayed puberty in rats whose mothers consumed Hibiscus sabdariffa during lactation. Pharmaceutical Biology 48 (10): 1170-1176.
- IYARE, E. E., ADEGOKE, O. A. and NWAGHA, U. I. (2010): Mechanism of the decreased food consumption and weight gain in rats following consumption of aqueous extract of the calyx of Hibiscus sabdariffa during pregnancy. Asia Pacific Journal of Tropical Medicine 3(3): 185-188.
- NWAGHA, U. I., OKEJI, N., CLEMS-ANUNWA, O., EJEZIE, F. E., NWAGHA, T. U. and IYARE, E. E. (2010): The role of some micronutrients (Eldervit-12 in the management of anaemic pregnant Nigerian women: A preliminary report. Tropical Journal of Obstetrics and Gynaecology. Tropical Journal of Obstetrics and Gynaecology. 27 (2): 34-39.
- IYARE, E. E. and ADEGOKE, O. A. (2011): Effect of lactational exposure to an aqueous extract of Hibiscus sabdariffa on body mass index at onset of puberty in female Sprague-Dawley rats. Pakistan Journal of Nutrition 10 (4): 360-364.
- IYARE, E. E. and ADEGOKE, O. A. (2011): Gestational outcome in rats that consumed aqueous extract of Hibiscus sabdariffa during pregnancy. Pakistan Journal of Nutrition 10 (4): 350-354.
- NWAGHA, U. I., IYARE, E. E., EJEZIE, F. E., OGBODO, S. O., DIM, C. C.and ANYAEHIE, B. U. (2012): Parity related changes in obesity and some antioxidant vitamins in non-pregnant women of South Eastern Nigeria. Nigerian Journal of Clinical Practice 15 (4): 380-384.
- OKEREKE, C., OKEKE, T. C., ANYAEHIE, B. U., NWAGHA, U.I., IYARE, E. E., NWOGU-IKOJO, E., and ORIZU, I. A. (2012): The effect of gravidity on anthropometric indices of pregnant women in Enugu, South East Nigeria. African Journal Biomedical Research. 15; 165-170.
- IYIDOBI, E. C., ANYAEHIE, U. S. B., IGWEH, J. C. and IYARE, E. E. (2013): Leukocyte profile of adult Nigerian subjects with acute musculoskeletal trauma. Nigerian Journal of Medicine 22(1): 32-36.
- NWAGHA, U. I., IYARE, E. E., OGBODO, S. O., AGU, P. U., OLUBOBOKUN, T. H., EZEONU, P. O. and ONYEBUCHI, A. K. (2013): Parity-related changes in body weight may influence the zinc and copper status of urban pregnant women: a report from south eastern Nigeria. Journal of Basic and Clinical Reproductive Sciences 2(1): 32-37.
- OLUBOBOKUN, T. H., ALUKO, E. O., IYARE, E. E. and ANYAEHIE, U. B. (2013): Dioscorea alata reduces body weight by reducing food intake and fasting blood glucose level. British Journal of Medicine and Medical Research 3(4): 1871-1880.
- NUBILA, T., UKAEJIOFO, E. O., NUBILA, N. I., IYARE, E. E., SHU, E. N., CHIJIOKE, C.P. and IBOK, I. F. (2013): Subacute effects of Methanolic crude leaf extract of Gnetum africanum on the haematological profile in albino Wistar rats. International Journal of Aromatic Plants 3 (2): 220 -225.
- OLUBOBOKUN, T. H., ALUKO, E. O., IYARE, E. E., ANYAEHIE, U. B. and ATANG, D. E. (2013): Ipomoea batatas extract reduces food intake, fasting blood glucose levels and body weight. European Journal of Medicinal Plants 3(4): 530-539.
- SORONNADI, C. N., ANYEHIE, B. U., IYARE, E. E., NEBOH, E. E., ODIEGWU, C. N. C. and ODURUKWE, O. (2013): Oral supplementation of vitamin C reverses haemostatic dysfunction in chronic smokers. Biomedical Research 24 (4): 458-462.
- NUBILA, T., UKAEJIOFO, E. O., NUBILA, N. I., SHU, E. N., OKWUOSA, C. N., UKAEJIOFO, A. C., IYARE, E. E. and OGBUTA, O. I. (2013): Effects of Methanolic seed extract of Telfairia occidentalis on blood coagulation in albino rats. Nigerian Journal of Experimental and Clinical Biosciences 1 (1 and 2): 10-13.
- NUBILA, T., UKAEJIOFO, E. O., NUBILA, N. I., IYARE, E. E., CHIJIOKE, C. P., UKAEJIOFO, A. C., SHUNEBA, I. L. and AGUNBAH, S. J. (2013): Methanolic crude leaf extract of Ocimum gratissimum reverses phenylhydrazine-induced anemia in albino Wistar rats. Nigerian Journal of Experimental and Clinical Biosciences 1 (1 and 2): 23-27.
- NUBILA, T., UKAEJIOFO, E. O., NUBILA, N. I., OKWUOSA, C. N., CHIJIOKE, C. P., SHU, E. N.and IYARE, E. E. (2013): Subacute effects of crude Methanolic leaf extract of Mucuna flagellipes (Vogel ex Hook) on haematological profile and haematinic activities in albino Wistar rats. International Journal of Medicinal and Aromatic Plants 3 (4): 452-458.
- OKEREKE, C. E., ANYAEHIE, B. U., DIM, C. C., IYARE, E. and NWAGHA, U. I. (2013): Evaluation of some Anthropometric Indices for the Diagnosis of Obesity in Pregnancy in Nigeria: A cross-sectional study. African Health Sciences 13(4): 1034-1040.
- NUBILA, T., UKAEJIOFO, E. O., IKE, S. O., SHU, E. N., NUBILA, N. I., CHIJIOKE, C. P., UKAEJIOFO, A. C., IYARE, E. E., OKWUOSA, C. U. and OKWUOWULU, O. V. (2014): Predisposing factors associated with uncomplicated type-2 diabetes among adults in a diabetic clinic, Enugu state, Nigeria. Transactions of the Royal Society of Tropical Medicine and Hygiene 108 (4): 206-212.
- IYARE, E. E. and OBAJI, N. N. (2014): Effects of aqueous leaf extract of Azadirachta indica on some haematological parameters and blood glucose level in female rats. Nigerian Journal of Experimental and Clinical Biosciences 2 (1): 54-58.
- NWAGHA, U., IYARE, E., ANYAEHIE, U., ONYEDUM, C., OKEREKE, C., AJUZIEOGU, O., AMUCHEAZI, A., OLUBOBOKUN, T., AGU, P., IGWEH, J. and OGUANUO, T. (2014): Forced expiratory volume in 6 s FEV6) and FEV1 /FEV6 values as a viable alternative for forced vital capacity (FVC) and FEV1/FVC values during pregnancy in South East Nigeria: A preliminary study. Annals of Medical and Health Sciences Research 4:516-21.
- OLUBOBOKUN, T. H., ALUKO, E. O., IYARE, E. E., ANYAEHIE, U., OLATUNBOSUN, E. D. and AIZENABOR, G.I. (2014): Aqueous extract of Ipomoea batatas reduces food intake in male wistar rats: A pilot study. Ann Med Health Sci Res 4:647-9.
- ANYAEHIE, U. B., OKEKE, T., NWAGHA, U., ORIZU, I., IYARE, E., DIM, C. and OKAFOR, C. (2014): Impact of some low-cost interventions on students performance in a Nigerian medical school. Nigerian Journal of Clinical Practice 17(5): 555-558.
- IYARE, E. E., OBAJI, N. N., EZEH, C. O., NUBILA, T. and ORIZU, I. A. (2014): Effect of Consumption of aqueous extract of Azadirachta indica during pregnancy on pregnancy outcome in rats. Pensee Journal 76 (9): 308-316.
Books
- IYARE, E. E. (2009): Gastrointestinal Physiology. In: Fundamental Multiple Choice Questions In Medical Physiology With Answers And Comments. Edited by Dr. Uchenna Ifeanyi Nwagha. Published by Ezu Books Ltd, Enugu, Nigeria. Chapter 6, pages 83-104.
- IGWEH, J. C., UDE, J. F., NWAGHA, U. I., NWACHUKWU, D. C., ORIZU, I. A., IYARE, E. E. and NWEKE, M. L. (2005): Experimental Physiology for Medical and Allied students. ISBN 978-36988-O-X. Chenglo press, Enugu, Nigeria.
Thesis/Projects
- Impact Of Hibiscus Sabdariffa Calyx Aqueous Extract Consumption By Pregnant And Lactating Sprague-Dawley Rats On Pregnancy Outcome And Postnatal Development. Ph.D thesis, 2010, Dept of Physiology, College of Medicine, University of Lagos, Nigeria.
- Fasting Plasma Glucose And Cholesterol Levels In Pregnant Nigerian Women. M.Sc. Dissertation, 2000, Dept of Physiology, College of Medicine, University of Lagos, Nigeria.
- Assay Of Testosterone And Progesterone For Glucocorticoid Or Antiglucocorticoid Activities In Vivo. B.Sc. Project, 1997, Dept of Physiology, College of Medicine, University of Lagos, Nigeria.
IYARE, FESTUS EHIGIATOR
ASSOCIATE PROFESSOR OF PATHOLOGY
DEPARTMENT OF PATHOLOGY
EBONYI STATE UNIVERSITY/FEDERAL TEACHING HOSPITAL, ABAKALIKI
PMB 53/PMB 102, ABAKALIKI 480001
EBONYI STATE, NIGERIA
- PERMANENT HOME ADDRESS: 113, EKEHUAN ROAD,
PO BOX 6466, BENIN-CITY
EDO STATE, NIGERIA
- EMAIL: festus_iyare@yahoo.com
- 234-803-7170172
- DATE OF BIRTH: 5TH JUNE 1958
- GENDER/NATIONALITY: M/NIGERIAN
- MARITAL STATUS/NUMBER OF CHILDREN: MARRIED/4
1. EDUCATIONAL BACKGROUND:
TYPE DATE INSTITUTIONS QUALIFICATIONS/DATE |
- PRIMARY 1966-1971 NBC PRY. SCH. B/C FLSC/1971
- SECONDARY 1972-1976 ICC, BENIN-CIYT WASC/1976
- POST SECONDARY 1976-1977 EDO COLLEGE, B/C ADVANCED LEVEL
- TERTIARY 1977-1978 UNIVERSITY OF LAGOS PRELIM MED./1978
- GRADUATE 1978-1983 COLLEGE OF MEDICINE(UNILAG) MBBS/1983
- 1990-1995 NPMCN/LUTH FMCPath./1995
. .
- WORK EXPERIENCE:
- Housemanship: In specialist Hospital, Benin City, Nigeria (Nov. 1983 – Nov. 1984)
Job Description: Rotate through the four major departments of 3 Month duration each that is, Department of MEDICINE, SURGERY, OBSTETRICS & GYNAECOLOGY and PAEDIATRICS. This Period also include posting to the Casualty Sections of the relevant Departments.
- National Youth Service In Birnin-Kudu General Hospital, Kano, Kano State Nov. 1984 to Nov. 1985
Job Description: Worked as Senior House Officer and the first point of contact with Medical Doctor by almost all patients that come to hospital. I was in charge of the management of most patients seen by me Including Medical, Surgical (including surgeries) Obstetric, Gynaecological and Paediatric problems and Emergencies
- Medical Officer: In charge of St. Mary’s Hospital, Okpoga (Catholic Diocese of Makurdi), Benue State November 1985 to August 1987.
- Senior Medical Officer: In charge of St. Damian’s Hospital, Okporo (Catholic Diocese of Orlu), Imo State between September, 1987 and January, 1990.
Job Description: I was in charge of all Medical, Surgical, Obstetric & Gynaecoogy and Paediatric problems of patients including minor and or major surgical Procedures like Spelenectomies, Intestinal resection and anastomosis, Cesaerian Sections, Hystrectomies, Herniorrhaphies,Appendectomies where necessary. This also includes some Administrative responsibility for the hospital regarding medical matters. These Hospitals are situated in the rural and peri-urban areas of the respective states of Nigeria.
2a. Registrar: In Morbid Anatomy/Histopathology of the
Department of Morbid Anatomy of Lagos
University Teaching Hospital between February,
1990 and June 1992.
Job Description:
- To perform and interpret gross and microscopic findings on almost all autopsies including difficult cases.
- To interpret and report the majority of cytology cases.
- To assist in the training of first year residents and Medical students.
- To present material at departmental and hospital rounds including clinicopathologic conferences.
- Interpretative autopsy demonstration to medical students, Clinicians and Surgeons in relevant cases.
- Organisation of resident seminars, journals clubs, etc
- To undertake rotations of 3 months each and participate actively in the routine and other works of the other branches of pathology; viz: Microbiology and Parasitololgy,Chemical Pathology and Haematology and Blood Transfusion.
2b. SENIOR REGISTRAR in Morbid Anatomy/Histopathology Department of
Lagos University Teaching Hospital
Job Description:
- In addition to the duties of Registrar, I am to perform the following duties among many others:
- To perform and interpret gross and microscopic findings on all autopsies especially difficult and special cases involving special techniques.
- To perform in the training of first year, second year residents, and medical students.
- To interpret and report all cytology cases.
- To conduct research and present papers/materials for publications in journals and scientific conferences.
2c. CHIEF REDIDENT: In Morbid Anatomy/Histopathology Department of
Lagos University Teaching Hospital
Job Description:
- In addition to the duties as Senior Registrar, I am to oversee the smooth running of the various routine duties of each Resident and other duties assigned by the Head of Department
2d. CONSULTANT PATHOLOGIST/CHIEF MEDICAL OFFICER
St. Damian’s Hospital, Okporo-Orlu, Imo State May 1995 till 2004
Job Description
* Supervise other Medical Doctors
* Organise and supervise the Medical/Surgical; Services
* Organise and supervise the Maternity & Child welfare services
* Organise and Supervise the Primary health care Home/Health. Outpost visiting services
* Supervise Laboratory services
* Supervises the ultrasonography/Imaging Unit
* Report on all Biopsy/Cytology Specimens.
* Interpret all Autopsies.
* Organise and supervise the mortuary and funeral services unit
* Organise and Supervise the Cancer Screening Programme of the Diocesan Health Services.
* Other duties assigned by the Diocesan Health Management Committee
2e. CHIEF CONSULTANT PATHOLOGIST/ASSOCIATE PROFESSOR OF PATHOLOGY
Federal Teaching Hospital/Ebonyi State University, 2005 – /2011 – till date
Job description
* Organize and provide histopathology services
* Organize and provide cytology services
* Train resident doctors in pathology
* Teach medical, nursing science, medical laboratory science, and anatomy students’ pathology
* Research and administrative duties
- MEMBERSHIP OF PROFESSIONAL BODIES:
- Nigerian Medical Association
- Fellow of National Postgraduate Medical College of Nigeria
- Association of Pathologists of Nigeria.
- Medical and Dental Consultants of Nigeria(MDCAN)
- Fellow international college of surgeons
- West African division of international academy of pathology
- PREVIOUS POPSITIONS HELD:
- i) Director of Pathology Services and Cancer Screening Center at St. Damian’s Hospital, Okporo-Orlu, Imo State. 1995-2001
- ii) Head of Department of Pathology, Abia State University, Uturu, Abia State, Jan. 1996-Jan – Jan. 2001
iii) Lecturer in Anatomic Pathology/Forensic Medicine, Abia State University Jan. 1996 – Jan. 2001
- iv) Consultant Histopathologist to the Abia State University Teaching Hospital Aba Jan. 1996 – Jan. 2001
- v) Visiting Senior Lecturer in Morbid Anatomy/Histopathology, Ebonyi State University Jan. 2000-2011
- vi) Visiting Honorary Consultant Pathologist to Ebonyi State University Teaching Hosp. Jan. 2000-2011
vii) Senior Consultant Pathologist, Federal Medical centre, Abakaliki April 2001 – March 2005
viii) Chief consultant Pathologist, Federal Medical Centre, Abakaliki April 2005 – September 2011
- ix) Head of Dept. Morbid Anatomy/Histopathology, EBSU, 2000-2001, 2007-2008, 2013-Aug. 2014
- x) Head of Dept. Haematology & Blood transfusion, EBSU, 2001-2002
- xi) Head of Dept. Chemical Pathology, EBSU, 2011-2013
xii) Coordinator of Residency Training Program, FETHA, 2012 – July 2014
xiii) Sub Dean, Faculty of Clinical Medicine, CHS, EBSU, 2012 – July 2014
5. CURRENT POSITIONS:
* Examiner in Faculty of Pathology, NPMCN, 2005 – till date
* Chief Consultant Pathologist, FETHA, October, 2011 – till date
* Associate Professor of Pathology, EBSU, October, 2011 – till date
* Member Learning Resources Committee of NPMCN, 2011 – till date
* Chairman, Faculty Curriculum Committee, FCM, EBSU, 2012 – till date
* Head of Dept. Pathology, EBSU, 1st August, 2014 – till date
- OTHER ACTIVITIES:
* President,Federated ( EBSUTH) Staff Credit & Thrift Cooperative Society Ltd. 2011-till date
- SELECTED WORKSHOPS AND COURSES:
* European Advanced Postgraduate Course in Classical and Molecular Cytogenetics, Nimes, France, 3rd – 11th March 2014
* The Contribution of Anatomic Pathology to health of women and children, Harvard Medical School, 4th – 8th November, 2013
* Advanced Research Methodology Course, National Postgraduate Medical College of Nigeria, 4th -6th July 2012
* Human Subject Protection, Protocol Review and community engagement in research, Abakaliki, 25th – @8th May, 2011
* Train the Trainers Workshop in Modern Docimology Methods, 22nd – 26th September 2010
REFEREES:
- Prof. C. O. O Chukwu Former, Federal Minister of Health
Federal Ministry of Health
Abuja, Nigeria
234-08037621816
234-08036660605
- Prof. C.A. Attah College of Health Sciences
Ebonyi State University, PMB 077
Abakaliki, 480001
Ebonyi State – Nigeria
234-8034101232
- Prof. E. U. Ajuluchuku College of Health Sciences
Ebonyi State University
Abakaliki, 480001
Ebonyi State, Nigeria
234-8033944611
LIST OF PUBLICATIONS
- Iyare F. E. Endometrial biopsy and histopathological diagnosis: A 10 year review. JOMIP Vol. 1 Nov 2000: 13
- Iyare F. E. Advanced Abdominal Pregnancies at St. Damian’s Hospital, Orlu, Nigeria. Journal of Health and Visual Sciences (3), 2001: 19-23.
- Iyare F. E. Breast Cancers in Orlu, Nigeria. Journal of Health and Visual Sciences (3), 2001: 31-35.
- Iyare F. E. Diseases of the male breast. Journal of Health and Visual Sciences (3), 2001: 36-38.
- Iyare F. E. Patterns of cancers in Orlu, Nigeria. Journal of Health and Visual Sciences (3), 2001:
- Iyare F. E. Tumours of the breast in Orlu, Nigeria. Journal of Health and Visual Sciences (4), 2002:
- Iyare F. E., Ikerionwu S.E., Emedike S.O.C. Leiomyomatosis peritonealis disseminate in a Nigerian male. Journal of Health and Visual Sciences (5), 2003: 71-75.
- Iyare F. E. Menstruation and its associated perculiarities in Nigerian Girls. Journal of Health and Visual Sciences (6), 2004: 1-6.
- Amadife M.U, Iyare F.E. The need for high index of suspicion in early diagnosis of typhoid fever in young children. Nigerian Journal of Medicine, 2006
- Onuoha C.E.O, Iyare F.E. Dicephalic-dipus: A case report. West African Journal of Medicine 25 (2); 2006: 161-163.
- Ajuluchuku E.U, Imo A.O.C, Iyare F.E. Unusual presentation of greater curvature omental cyst. Ebonyi Medical Journal 5 (1); 2006: 28-31
- Iyare E.E, Iyare F.E. Effect of inutero exposure to an aqueous extract of hibiscus sabdariffa on offspring’s postnatal growth in Sprague-Dawley rats. Nigerian Journal of Health and Biomedical Sciences 5 (1); 2006: 27-30
- Iyare E.E, Iyare F.E. Lactational exposure to an aqueous extract of hibiscus sabdariffa (HS) accelerates offspring’s early postnatal growth in Sprague-Dawley rats. J. Expt. & Clin. Anat. 5(1); 2006: 6-9.
- Iyare E.E, Iyare F.E. The Effect of an aqueous extract of hibiscus sabdariffa on gestational weight gain, pregnancy outcome and postpartum weight retention in Sprague-Dawley (SD) rats. Nigerian Journal of Health and Biomedical Sciences 5 (2); 2006: 26-29.
- Uneke C.J, Sunday-Adeoye I, Iyare F.E, Uguja E.I, Duhlinska D.D. Impact of maternal plasmodium falciparum malaria and haematological parameters on pregnancy and its outcome in southeastern Nigeria. J Vector Borne Dis 44; 2007: 285-290.
- Iyare F.E. Mixed mesodermal tumour of the ovary coexisting with adenocarcinoma of the ileum in a postmenopausal Nigerian woman. Ebonyi Medical Journal 6 (2); 2007: 114-117
- Iyare E.E, Iyare F.E. Maternal consumption of aqueous extract of hibiscus sabdariffa during pregnancy attenuates pregnancy weight gain and postpartum weight loss. Afr. J. Biomed. Res. 10; 2007: 257-261
- Iyare F.E. Immunohistochemical characteristics of breast cancers in south east Nigeria. Ebonyi Medical Journal 6 (1); 2007: 9-12.
- Uneke C.J, Iyare F.E, Adeoye I.S, Ajayi J.A. Evaluation of maternal malaria at childbirth using rapid diagnostic test and its relationship with birth weight and fetal hemoglobin levels in Nigeria. The Internet Journal of Gynecology and Obstetrics 10 (1); 2008.
- Iyare E.E, Iyare F.E. The Effect of prenatal and postnatal exposure to an aqueous extract of hibiscus sabdariffa (HS) on postnatal growth in Sprague-Dawley rats. Pakistan Journal of Nutrition 7 (2); 2008: 255-257.
- Uneke C.J, Iyare F.E, Sunday-Adeoye I, Ajayi J.A. An assessment of the impact of placental plasmodium falciparum malaria on perinatal outcome in Nigeria. The Internet Journal of Parasitic Diseases 3 (2); 2008.
- Uneke C.J, Iyare F.E, Oke P, Duhlinska D.D. Assessment of malaria in pregnancy using rapid diagnostic tests and its association with HIV infection and hematological parameters in south-eastern Nigeria. Haematologica. 93 (1); 2008: 143-144.
- Iyare F.E. Diseases of the prostate among Igbos of southeastern Nigeria. Ebonyi Medical Journal 7 (1&2); 2008: 8-13.
- Huo D, Ikpatt F, Khramtsov A, Dangou JM, Nanda R, Dignam J, Zhang B, Grushko T, Zhang C, Oluwasola O, Malaka D, Malami S, Odetude A, Adeoye AO, Iyare FE, Falusi A, Perou CM, Olopade OI. Population differences in breast cancer: Survey in indigenous African women reveals overrepresentation of triple negative breast cancer. J Clin Oncol. 27(27); 2009: 4515-4521.
- Iyare F.E, Iyare E.E, Adegoke O.A. Morphologic changes in the utero-ovarian tissues of the offsprings of rats exposed to aqueous extract of hibiscus sabdariffa during lactation. J.Expt. & Clin. Anat. 8(2): 10-15
- Agwu UM, Umeora OUJ, Ogbonnaya LU, Iyare FE, Obuna JA, UMahi G, Egwuatu VE. Fetal Umbilical Cord length and associated Intrapatrum complications in a tertiary institution, Southeast Nigeria, Ebonyi Medical Journal. 9(2); 2010: 112-118
PUBLISHED BOOKS
- That We May Live and Be Free (A patho-scriptural peep into the death of Jesus Christ on the cross), 1999, Charismatic Forum Publications Ltd. Owerri
- Pathological Sciences: MCQ guide to medical students, 1999, K.K Integrated Systems, Owerri.
- Pathological Sciences: Review Objective Tests for Medical Students, 2005, Bills Prints & Publishers, Amawbia, Anambra State.
- The Medical Witness, 2008, Larry & Caleb, a Copycraft International company, Abakaliki.
CHARLES OGBONNA EZEH
Department of Medical Biochemistry, Faculty of Medical Sciences, College of Medicine, University of Nigeria, Enugu Campus, Enugu, Nigeria.
E- mail: charlesezeh@yahoo.com, charles.ezeh@unn.edu.ng
Phone: +234(0)803709312, +234[0]8163772395
PERSONAL DATA
Sex: Male
Current Position: Lecturer I
State of Origin: Enugu State
Date of Birth: 25th August, 1972
Local Govt. Area: Uzo-Uwani
EDUCATION
University of Port Harcourt, Port Harcourt (Ph.D) Biochemistry- 2009
University of Port Harcourt, Port Harcourt (M.Sc.) Biochemistry- 2005
University of Nigeria, Nsukka Campus (B.Sc.) (Hons) Biochemistry- 1997
St. Teresa’s College Nsukka.(Senior School Certificate/G.C.E.)- 1990
THESIS/DISSERTATION
- Applications of some plant peroxidases in Bread Baking. Pulp and Paper Processing.-Ph.D Dessertation
- Comparative study of some properties of peroxidase from black beans (Phaseolus vulgaris and Pigeon pea (Cajanus cajan).-M.Sc. Thesis
- Some Properties of Sorgum and Rubber seed Peroxidases.-B.Sc.
PUBLICATIONS
- Obiekezie SO, Ezeh CO, Okhiai O, Verla AW (2007)
Preliminary Investigations on the phytochemical and antibacterial activities of inyi plant leaves (Erthrophleum suaveloens) Int. J. Biotechnol & Allied Sc 2(3): 272-274.
- Obiekezie, S. O. Eze, C. O., Ibegbulam, G.O. and Verla, A. W (2007)
Seasonal variation of levels of toxic/Heavy metal of Bilante rock mining pit water Ishiagu, Ebonyi State(2007). Int J Biotechnol & Allied Sc 2(3) : 297-299.
- Ezeh CO, Ubenyi SM, Nweke ML. (2009) Antisickling effect of Aloe vera extract on sodium metabisulphite induced sickling on human erythrocytes Int. J. Biotechnol& Allied Sc 4(1) 288-292.
- Ezeh CO, Ubenyi SM, Nweke ML. (2009) Effects of co-administration of chloramphenicol and garcinia Kola extract on liver and kidney functions of whistar rats. Int. J. Biotechnol. And Allied Sc 4(1): 233-240.
- Ezeh CO, Nweke ML, Ubenyi SM, (2009) Some changes ib biochemical parameters of kidney and liver functions in whistar rats co-administered with tarivid and garcinia kola extract Int. J. Biotechnol &Allied Sc 4(2): 193-199.
- Ezeh CO, Nweke ML, Ubenyi SM, (2009) Changes in some biochemical indices of liver and kidney functions of whistar rats co-administered with garcinia kola extract and halofantrine(antimalarial) Int. J. Biotechnol & Allied Sc 4(1): 87-94
- Ezeh CO, Akinwale, OP Shan L, Zhang T Zheng Q, Chitsulo L, Wei H (2012) Urinary schistosomiasis in Nigeria: A 50 years review of prevalence, distribution and disease burden-in Press
- Nweze EI, Ezute S, Emeka Nweze CC, Ogbonna CC, Eze C.O. (2012)
Bacteria etiological agents causing respiratory tract infections in children
and their resistance patterns to a panel of ten antibiotics Asian Pacific Journal
of Tropical Disease, 18-23.
BOOKS
- Ezeh, C.O. and Ude, C. M (2006) Essentials of Enzymology. JTC Publishers ISBN: 978-35036-3-4
- Ezeh, C.O. Achikanu, C.E and Amadife, (2006) Introductory Biochemistry . His Glory Publications ISBN: 978-37896-7-8
- Ezeh, C. O.(2006 Revised 2010) Senior Secondary School Chemistry Practical Manual/Workbook EMC &CO Nig. ISBN:97835328-2-0
EXPERIENCES/Membership OF SOCIETIES
Post Doctoral Fellow April-2012- March 2013-National Institute of Parasitic Diseases, Chinese
Centre for Disease Control, Shanghai, China.
Lecturer 1-October 2011-Date – Department of Medical Biochemistry, College of Medicine, University of Nigeria, Enugu Campus.
Lecturer 11- September, 2008 – September 2011 Department of Medical Biochemistry, College of Medicine, University of Nigeria, Enugu Campus.
Assistant Lecturer –February, 2007-September, 2008- Department of Medical Biochemistry, College of Medicine, University of Nigeria.
Secretary NUGA UNN HIV/AIDS Awareness Committee-2009
Coordinator Post Graduate Programs Medical Biochemistry Department University of Nigeria Enugu Campus 2010-2013.
Member Nigerian Society of Biochemistry and Molecular Biology 2008 – Date
Member British Biochemical Society 2008 – Date
Research Fellow Chinese Institute of Parasitic Diseases 2012- Date
Member Nigerian Red Cross Society 2011-Date.
TRAINING ATTENDED
- Participated in the research team on stigma and discrimination in Enugu State. 2008
- Gender mainstreaming and HIV/AIDS in the Hospital section. Organized by UNICEF in Enugu 2007.
- International Union of Biochemistry and molecular Biology in conjunction with EMBO, ICGEB and FEBS organized training on “cellular and molecular basis of infectious diseases” held in Hermanus, Cape Town South Africa. 27th February – 11 March 2008.
CONFERENCES
1.IUBMB Advanced Summer School Organised in Hermanus Cape Town, South Africa 29th March-10th April 2008
Changes in some biochemical parameters of Kidney and Liver functions of whistar rats co-administered with Halofantrine and Garcinia Kola seed extract.
Ezeh, C. O. Ubenyi, S. M. Ogbunude, P. O. J. Nweke, M. Anyaechie, B. U. Ibegbu, D. M. Eze, A.A. and Iyare, E.E.
2.Zoological Society of Nigeria 4th Annual Conference Organised at Owerri, Imo State Nigeria 20th-24th Nov. 2007
Trace metals in Yoghurt, ice-cream and fura da nunu sold in Owerri, Imo State Obiekezie, S. O. Eze, C. O. Okhiai, O. and Verla, A. W
3 The first Forum on Surveillance and Response System leading to Tropical Diseases Elimination, Shanghai, China, 16-18th June, 2012
REFERENCES
- Prof. E. O. Anosike
Department of Biochemistry
Faculty of Science
University of Port Harcourt
Port Harcourt.
- Prof. P. O. J. Ogbunude
Medical Biochemistry Department
Faculty of Medical Sciences
College of Medicine
University of Nigeria
Enugu Campus.
- Prof. Hu Wei
National Institute of Parasitic Diseases
Chinese Centre for Disease Control
Shanghai, China.
Full Name: OKOJIE Akhabue Kenneth
Date of birth: 2nd May, 1983
Nationality: Nigerian
Permanent home address: Thelver Pharmacy, Opposite University of Benin Teaching Hospital,
Along Ugbowo-Lagos Road, Ugbowo, Benin City, Edo State.
Current postal address: Department of Physiology, University of Nigeria, Enugu Campus, Enugu, Enugu State, Nigeria.
Phone Number: +2348063762090
Email: pintos4live@yahoo.com
Marital status: Single
Institutions attended with dates/Academic/professional qualifications
2012-Till Date: University of Nigeria, Enugu Campus, PhD Physiology (in progress)
2008-2010: University of Benin, Benin City, MSc Physiology.
2002-2005: Ambrose Alli University, Ekpoma, BSc (Hons) Physiology.
Work experience with dates
- 2012- Till Date: Biostatistics/Physiology Lecturer, School of Post Basic Nursing, University of Benin Teaching Hospital, Benin City, Edo Sate, Nigeria.
- 2010-2012: Medical Representative, Ranbaxy Nigeria Limited.
Courses/Workshop Attended
- Neurobiology of Disease Workshop: Human Brain Disorders in a Dish: Induced Pluripotent Stem Cell Models of Disease. San Diego, CA, USA. 8th Nov, 2013.
- IBRO workshop on “writing skills” Rabat, Morocco. 9th-12th June, 2013.
- 1st IBRO School on Insect Neuroscience and Drosophila Neurogenetics. School of Health Sciences, Kampala International University, Ishaka, Uganda. 20th August-7th September, 2012.
- IBRO School on Basic and Clinical Neurosciences. Ibadan, Nigeria. 5-9th December, 2011.
Conference Attended
- Society for Neuroscience. Washington, DC, USA, 15th -19th November, 2014
- Society of Neuroscientist of Africa. Rabat, Morocco, 13th-17th June, 2013.
Poster Presentation: Effects of induced pain on spatial memory in male Sprague dawley rats.
- Society for Neuroscience. San Diego, CA, USA, 9th -13th November, 2013. Poster Presentation: Ethanol-induced antinociception in male albino rats: Role of adrenergic blockers.
- Society for Neuroscience International Fellows Poster Session. San Diego, CA, USA, 9th November, 2013. Poster Presentation: Relationship between the plasma testosterone level and pain reaction times in male rats.
Awards
- November 2013: SfN/IBRO Travel Grant. To attend Society for Neuroscience Annual Meeting 2013, San Diego, California, USA.
- February 2014 – March 2014: ISN-CAEN Research grant to visit Prof. J. Attems and Dr. G. Saretzki’s Lab, Institute for Ageing and Health, Newcastle University, Newcastle, UK.
Membership of Professional Organization
- Member, Society of Neuroscientists of Africa (SONA)
- Member, International Society for Neurochemistry (ISN)
- Graduate Member, Society for Neuroscience (SfN)
Publications
- K. Okojie and O. A. Oyekunle (2013): Depo-Provera effects on Wistar rat performance in the Y-maze. Metab Brain Dis. DOI 10.1007/s11011-013-9460-9.
- I. Ebomoyi and A.K. Okojie (2012): Physiological Mechanisms underlying the use of Garcinia kola Heckel in the treatment of asthma. ARJM 8 (1): 5-8.
- Oko-ose J, Okojie A.K, Iyawe V.I (2011): Physiological basis of pregnancy inducedhypertension. Journal of Medicine and Medical Science; 2(7): 939-945.
- AOyekunle, T.P Ogundeji and A.K. Okojie (2011): Behavioral modifications related toconsumption of a “soft” adaptogen, Bee Honey, by rats. Neurophysiology; 43 (1):46 – 50.
- AOyekunle, A.K. Okojie and U.S. Udoh (2010): Anagelsic and anti-inflammatory effects ofan extract of FadogiaAgrestis in rats. Neurophysiology; 42 (2):147 –151.
- AOyekunle, G.F Ibironke, S.F. Ige, U.S. Udoh and A.K. Okojie (2009): Relationshipbetween the plasma testosterone level and pain reaction times in male rats. Neurophysiology; 41(3):231 – 234.
- Udoh U S, Oyekunle O A, Ige S F, Okojie A K, Ogunwale E B (2009): Effect of oraladministration of aqueous kola nut extract (Kola nitida) on reproductive hormones in maleSprague dawley rats. Afr.J.MedSci; 2(2):31-34.
- Okojie A.K., Nwaokpara A.O. and Ute I (2008): Seasonal variation of blood pressure in firstpregnancies. J. Med. Pharm, Sci; 4 (1): 1 – 4.
- Okojie A.K., Dibie D.C and Inegbenebor U (2008): Pathophysiological implications of Obesity and its relationship with diabetes mellitus. J. Advan. Med. Pharm. Sci., 2(4): 16-18.
Service to Nation
2007-2008: National Youth Service Corp (NYSC), Technology Assistant, Department of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.
Extra-curricular activities
Reading, Surfing, Football and Chess.
Names and addresses referees
Dr. E. Iyare
Department of Physiology
University of Nigeria
Enugu Campus
Enugu Sate. Nigeria.
Dr. G. Saretzki
Lecturer in Ageing Research
Institute for Ageing and Health
Campus for Ageing and Vitality
Edwardson Building
Newcastle upon Tyne, NE4 5PL, UK
+441912481214
Dr. Ute Inegbenebor
Department of Physiology
College of Medicine
Ambrose Alli University
Ekpoma, Edo State, Nigeria.
PERSONAL DATA
Name: Morufu Eyitayo BALOGUN
Gender: Male
Date of Birth: June 1, 1976
Place of Birth: Iseyin, Oyo state
Marital Status: Married
Nationality: Nigerian
State of origin: Oyo
Local Government Area: Iseyin
Permanent Home Address: Alagbede Compds, Ago-Ijemba, Iseyin, Oyo State
Present contact Address: No. 2, Nwankwo Street, Abakaliki, Ebonyi state
Present Postal Address: P.M.B 053, Physiology Dept., Ebonyi State University
E-Mail Address: marufbalogun@yahoo.com
Phone Numbers: +234-8104031671, +234-8037719726
EDUCATIONAL BACKGROUND
- Educational Institutions Attended (With Dates):
University of Nigeria, Nsukka, Enugu state 2013-Till date
University of Ibadan, Nigeria 2008 – 2010
University of Ilorin, Ilorin, Kwara State 1997 – 2003
Iseyin District Grammar School, Iseyin, Oyo State 1989 – 1994
Koso Community Primary School, Iseyin, Oyo State 1982 – 1988
- Academics and Professional Qualifications Obtained (With Dates):
PhD in Human Physiology (Nigeria) In-view
- Sc. in Human Physiology (Ibadan) 2010
- Sc (Hons.) in Human Physiology (Ilorin) 2003
West African Senior Secondary School Certificate 1994
Primary School Leaving Certificate 1988
WORKING/ TEACHING EXPERIENCE (WITH DATES)
Anatomy & Physiology Tutor
School of Health Technology,
Port Harcourt, Rivers State 2003 – 2004
Biology Teacher
St, John’s Catholic Grammar School,
Iseyin, Oyo State 2004 – 2005
Biology Teacher
Kelani College,
Iseyin, Oyo State 2005 – 2008
Practical Demonstration to
200L Medical Students, University of Ibadan, Ibadan 2008 – 2010
Part time Lecturer
School of Basic Midwifery,
Saki, Oyo State 2009 – 2011
Assistant Lecturer
Department of Physiology,
College of Health Sciences,
Ebonyi State University, Abakaliki 2011-2012
Lecturer II
Department of Physiology,
College of Health Sciences,
Ebonyi State University, Abakaliki 2012-Till date
ACADEMIC PUBLICATIONS (WITH DATES)
Thesis / Dissertations
- Is ethanol induced–ulceration affected by Chloroquine
administration in rats? (A Research Project Submitted to the
Department of Physiology, University of Ilorin) 2003
- The effect of Aqueous and Methanolic Extracts of Persea
americana on Gastric Acid Secretion in rats. (A Dissertation
Submitted to the Department of Physiology, University of Ibadan) 2010
Research and Publications:
- Balogun M. E., Jeje S. O., Salami S. A., Onwe P. E. and Folawiyo M. A. (2015). Anti-ulcerogenic and gastric anti-secretory effects of Nauclea latifolia extract in male albino rats. J. Exp. Biol. 5 (2): 74-80.
- Balogun M. E., Nwachukwu D. C., Onwe P. E. and Folawiyo M. A. (2014). Gastric acid anti-secretory effect of aqueous leaf extract of Nauclea latifolia (Rubiaceae) in rats. Phytopharmcol.3 (6): 389-394.
- Balogun M. E., Folawiyo M. A., Besong E. E. and Jeje S. O. (2014). Effects of ethanolic fruit extract of Adenopus breviflorus (Lagenaria breviflora) on hematological indices in male albino rats. Physiol. Pharm. Adv. 4 (11): 501-508.
- Balogun M. E., Ajayi A. F., Oji O. J., Bessong E. E., Finbarrs-Bello E. and Folawiyo M. A. (2014). Toxicological and biochemical studies of ethanolic fruit extract of Adenopus breviflorus (Lagenaria breviflora Roberty) in male albino Wistar rats. J. Phytomed. Clin. Therap. 2 (9): 1112-1123.
- Oluwole F. S., Balogun M. E., and Adedeji G. T. (2013). Antisecretory effects of water melon (Citrullus lanatus) juice in male albino rats. Rev. Res. Biol. 3 (4): 358-366.
- Balogun M. E., Oji J. O., Besong E. E, and Umahi G. O. (2013). Evaluation of the antiulcer properties of aqueous leaf extract of Dialium guineense (Velvet Tamarind) on experimentally induced ulcer models in rats. J. Dev. Res. 3 (10): 106-110.
- Balogun M. E., Oji J. O., Besong E. E., Ajah A. A. and Michael E. E. (2013). Anti-ulcer activity of aqueous leaf extract of Nauclea latifolia (rubiaceae) on indomethacin- induced gastric ulcer in rats. J. Biotechnol. 12(32): 5080-5086.
- Oji J. O., Balogun M. E., and Besong E. E. (2012). Effect of Quarry dust on the lung function and leucocytes pattern in albino Wistar rats. Biomed. Sci. Afr. 10 (1&2): 40-42.
CONFERENCES/WORKSHOP ATTENDED (WITH DATES)
- 32 ND Annual Scientific Conference of Physiological Society of Nigeria (PSN), 22-24th August, 2012, University of Calabar, Nigeria
- Grantsmanship Training Workshop, 11-12th February, 2014, Organized by Directorate of Research, Innovation & Commercialization (EBSU–DRIC), Ebonyi State University, Nigeria.
- Statistical Analysis of Data Training Workshop, 5-7th August, 2014, Organized by Directorate of Research, Innovation & Commercialization (EBSU–DRIC), Ebonyi State University, Nigeria.
- Quality Assurance Workshop/Training, Organized by National Universities Commission (NUC), 8-9th October, 2014, Ebonyi State University, Nigeria.
- TETFund Proposal Development Training Workshop, 23rd March, 2015, Organized by Directorate of Research, Innovation & Commercialization (EBSU–DRIC), Ebonyi State University, Nigeria.
STUDENTS SUPERVISION
- Anti-ulcer activity of aqueous leaf extract of Nauclea latifolia (rubiaceae) on indomethacin- induced gastric ulcer in rats. B.Sc. Project by Michael Emeka Michael, Department of Anatomy, Faculty of Basic Medical Sciences, Ebonyi State University, Abakaliki, Nigeria (2011/2012 session).
- Evaluation of the antiulcer properties of aqueous leaf extract of Dialium guineense (Velvet Tamarind) on experimentally induced ulcer models in rats. B.Sc. Project by Anikputa Daniel Chimdindu, Department of Anatomy, Faculty of Basic Medical Sciences, Ebonyi State University, Abakaliki, Nigeria (2012/2013 session).
- Effect of Quarry dust on the lung function and leucocytes pattern in albino Wistar rats. B.Sc. Project by Igwe Chidiebere, Department of Anatomy, Faculty of Medicine, Ebonyi State University, Abakaliki, Nigeria (2012/2013 session).
- Toxicological and biochemical studies of ethanolic fruit extract of Adenopus breviflorus (Lagenaria breviflora Roberty) in male albino Wistar rats. B.Sc. Project by Omabe Paul Chioma, Department of Anatomy, Faculty of Medicine, Ebonyi State University, Abakaliki, Nigeria (2013/2014 session).
- Effect of ethanolic fruit extract of Adenopus breviflorus (Lagenaria breviflora Roberty) on hematological parameters in male albino Wistar rats. B.Sc. Project by Anthony Paul Okoro, Department of Anatomy, Faculty of Medicine, Ebonyi State University, Abakaliki, Nigeria (2013/2014 session).
- Anti-ulcerogenic and gastric anti-secretory effects of Nauclea latifolia extract in male albino rats. B.Sc. Project by Nwachukwu Nancy Gift, Department of Anatomy, Faculty of Medicine, Ebonyi State University, Abakaliki, Nigeria (2014/2015 session).
CURRENT RESEARCH ACTIVITIES
- The main focus of my research activities is on the likely potency of herbal preparations äs a basis for anti-ulcer medication, and possible development of proto-type anti-ulcer drugs from herbal Also, dietary regimen in the prevention and amelioration of peptic ulceration. I hope to generate emperical data that can be subjected to clinical trials which will help in regulation and formulation of policies on incorporation of traditional medicine into Health Care delivery of my country.
DETAILS OF ADMINISTRATIVE EXPERIENCE
- Academic Course Adviser for 200L & 300L Medical Students, Faculty of Medicine, College of Health Sciences, Ebonyi State University, Abakaliki, Ebonyi State for (2012/2013) academic session.
- Academic Course Adviser for 400L Anatomy Students, Faculty of Medicine, College of Health Sciences, Ebonyi State University, Abakaliki, Ebonyi State for (2013/2014) academic session.
- Academic Course Adviser for 100L Medical Students, Faculty of Medicine, College of Health Sciences, Ebonyi State University, Abakaliki, Ebonyi State for (2014/2015) academic session.
PRESENT JOB STATUS
- Lecturer II, Department of Physiology, Faculty of Medicine, College of Health Sciences, Ebonyi State University, Abakaliki, Ebonyi State.
SKILLS AND ABILITIES
- Strong Fluent English written, oral, and presentation communication abilities
- Analytical and critical thinking skills
- Computer literacy
SERVICE TO THE COMMUNITY
Rectitude Society, Iseyin branch (Social Secretary)
- Organizing career talk in public and private secondary schools
- Enlightment programme on AIDS control and prevention
- Enlightened general public on sensitive societal issues such as Immunization
MEMBERSHIP OF THE PROFESSIONAL BODIES
- Physiological Society of Nigeria ( Member)
- Africa Physiological Society ( Member)
EXTRA CURRICULAR ACTIVITIES
Tennis, Traveling and Reading
REFERENCES
- Professor Y. Raji
Department of Physiology,
Faculty of Basic Medical Sciences,
College of Medicine,
University of Ibadan, Nigeria.
yoraji@yahoo.com, +234-8023263626
- Professor A. O. Afoke
Head, Department of Physiology,
Faculty of Medicine,
College of Health Sciences,
Ebonyi State University, Nigeria.
okoroafoke@yahoo.com, +234-8063918611
- Dr D. C. Nwachukwu, Senior Lecturer,
Department of Physiology,
Faculty of Medical Sciences,
College of Medicine,
University of Nigeria, Enugu Campus, Nigeria
danynwachukwu@yahoo.com, +234-8037245474
IGBERAESE CORDILIA OMUEKPEN
321,Borehole Road, Ekpoma, Edo State.
Email: cordie2age@gmail.com
Tel: 08131232377, 08055513314
PERSONAL DATA:
Date of Birth: 8th December, 1988
Sex: Female
Marital Status: Single
State of Origin: Edo State
Local Govt. Area: Esan Central
Nationality: Nigeria
EDUCATION:
University Of Nigeria Enugu in view
M.Sc Medical Physiology
Ambrose Alli University, Ekpoma 2006-2011
B.Sc Medical Physiology (Second Class Upper Division)
Ambrose Alli University, Ekpoma 1999-2005
(S.S.C.E)
Blessing Primary School, Ekpoma 1995-1999
(F.S.L.C)
WORK EXPERIENCE:
Editor,Annals of Health Sciences Research journal 2014-date
Editor, Journal of Basic and Clinical Reproductive Sciences 2014-date
Enugu State University College of Medicine 2011-2012
(NYSC)
Volunteer Work:
Community Development Service 2012
(Donation of Projectors to Enugu State College of Medicine)
REFEREES:
- Dr. Ute Inegbenebor
Dean FBMS,AAU,
Ekpoma, Edo State
+2348065278467
- Prof. Uchenna I. Nwagha
Dean,FMS, UNEC,
Enugu State
+2348033128233
- Dr. Eghosa E. Iyare
Physiology department,UNEC,
Enugu State
+2348052820041