REPRODUCTIVE AND DEVELOPMENTAL PROGRAMMING RESEARCH GROUP

 

REPRODUCTIVE AND DEVELOPMENTAL PROGRAMMING RESEARCH GROUP.

 

 

INTRODUCTION

 

It is beyond dispute that for each individual, the genetic endowment at conception sets the limits on the capacity for metabolic and reproductive function (Lau and Rogers, 2005). From a range of diverse fields including evolutionary ecology and molecular biology, however, it is now well established that the extent to which this capacity is achieved or constrained is determined by the environmental experience. The consequences of these experiences tend to be cumulative throughout life and express themselves phenotypically as achieved growth and body composition, hormonal status and the metabolic capacity for one or other function (Lau and Rogers, 2005).

 

At any time later in life, the response to an environmental challenge, such as stress, infection or excess body weight is determined by an interaction amongst these factors. When the metabolic capacity to cope is exceeded, the limitation in function is exposed and expresses itself as overt disease (Lau and Rogers, 2005). During early life and development the embryo, foetus and neonate are relatively plastic in terms of metabolic function (Lucas, 1991). The effect of any adverse environmental exposure is likely to be more marked than at later ages and the influence is more likely to exert a fundamental effect on the development of metabolic capacity. This has been characterized as “programming”-a process whereby a stimulus or stress at a critical period of development has lasting or lifelong significance (Lucas, 1991; Ross and Desai, 2005; Armitage et al., 2005).

Programming may result in altered cell number, organ structure, hormonal set points, and gene expression among others (Lau and Rogers, 2005). Although overt structural defects are usually associated with functional deficiency, the reverse is not necessarily true. Biochemical changes induced by prenatal and/or early postnatal insults that lead to physiological deficits of organ function may not always be accompanied by detectable anatomical abnormalities. Hence in recent decades, considerable attention has been drawn to functional teratology, an extension of the investigation beyond morphological examinations to include the evaluations of functional integrity of organ systems. Effects of programming may be permanent or expressed only at select offspring ages eg newborn, adult and may be dependent on the in utero environment eg nutrition, glucocorticoid or the early postnatal environment. Furthermore, expression of physiological abnormalities maybe present during basal conditions or restricted to environmental stress or disease states in the offspring (Lau and Rogers, 2005).

 

 

References

 

Armitage, J.A., Taylor, P.D., Poston, L. (2005). Experimental models of developmental programming: consequences of exposure to an energy rich diet during development

Journal of Physiology 15:565 (pt 1): 3-8

 

Lau, C. and Rogers, J.M. (2005). Embryonic and fetal programming of physiologic disorders in adulthood. Birth Defects Research (Part C) 72, 300-312.

 

Lucas, A. (1991). Programming by early nutrition in man. In Rock GR, Whelam J (eds): The childhood environment and adult disease (CIBA foundation symposium 156). Chichester:

Wiley 38-35

 

Ross, M.G. and Desai, M. (2005). Gestational programming: population survival effects of drought and famine during pregnancy. American Journal of Physiology Regulatory Integrative and Comparative Physiology 288: R25-33.

 

 

 

RESEARCH FOCUS:

 

To understand the mechanisms by which maternal perinatal nutritional perturbations program the development of the offspring phenotype with particular emphasis on the development and functioning of the reproductive system and the gut-brain nutrient sensing pathway.

 

 

OBJECTIVES

 

  1. To investigate how maternal perinatal nutritional perturbations affect placental development and function and how this relates to the offspring phenotype later in life (in the post-weaning period).
  2. To investigate the relationship particularly between the onset of puberty, mating behavior, pregnancy success rate, pregnancy outcomes and the development and functioning of the gut-brain nutrient sensing pathways in the offspring and maternal perinatal nutritional perturbations.

 

 

DESCRIPTION OF TEAM’S RESEARCH PLAN

 

The achievement of the research objectives will be based on the assessment of: 1) pregnancy and lactation outcomes in nutritionally perturbed dams and 2) offsprings’ postnatal growth, and the development and functioning of the reproductive system and the nutrient sensing pathways in the gut-brain axis.

 

The offsprings will at no time during their development be directly exposed to nutritional perturbations but will only be indirectly exposed through their mothers. These offsprings will be studied alongside their mothers in groups reflecting the periods during their development when they will be exposed to nutritional perturbations through their mothers. Postnatal growth and development will be assessed by measuring the weights and lengths of the offsprings, some growth promoting hormones as well as some internal organ weights and histologies at birth and then weekly until post-natal day 60. Onset of puberty will be assessed by determining the age in days at vaginal opening for the female offspring and balanopreputial separation for the male offspring. In adulthood, mating behaviours and reproductive success rates will also be assessed using established experimental reproductive techniques in rats. Development and functioning of the gut-brain nutrient sensing pathway will be investigated using established experimental protocols.

 

 

COMPOSITION OF GROUP

 

  1. Dr Eghosa E. IYARE (Coordinator)

Senior Lecturer,

Dept of Physiology,

College of Medicine, UNEC.

eghosa.iyare@unn.edu.ng

Phone: +2348052820041

 

  1. Dr Festus E. IYARE,

Associate Professor,

Dept of Pathology,

Ebonyi State University,

Abakaliki.

festus_iyare@yahoo.com

 

  1. Charles O. Ezeh,

Lecturer I,

Dept of Medical Biochemistry,

College of Medicine, UNEC.

charles.ezeh@unn.edu.ng

 

  1. Mr Kenneth A. Okojie,

Ph.D Student,

Dept of Physiology,

College of Medicine, UNEC.

pintos4live@yahoo.com

 

  1. Mr Maruf E. Balogun,

Ph.D Student,

Dept of Physiology,

College of Medicine, UNEC.

mafurbalogun@yahoo.com

 

  1. Miss Cordilia U. Igberaese,

M.Sc. Student,

Dept of Physiology,

College of Medicine, UNEC.

cordie2age@gmail.com

 

 

 

 

 

 research line

BRIEF CVs OF MEMBERS

 

 

Name: IYARE, EGHOSA EDORISIAGBON

Place and Date of Birth: Benin City, 2nd March, 1974

Age: 41 years

Present Postal/Email Address: Department of Physiology, College of Medicine, University of Nigeria, Enugu Campus, Enugu. eghosa.iyare@unn.edu.ng; gimagosa@yahoo.com

GSM number: 08052820041

Nationality: Nigerian

Marital Status: Married

Name and Address of Spouse: Dr (Mrs) Iyare, Oluwatoyin Ibukun, Department of Pathology, Federal Teaching Hospital, Abakaliki, Ebonyi State.

Number Of Children With Ages: Four (12years, 8years, 5years, 3years)

Next of Kin: Dr (Mrs) Iyare, Oluwatoyin Ibukun

Institutions Attended With Qualifications Obtained And Dates:

  1. Edo College, Benin City: Senior Secondary School Certificate (SSSC), 1992
  2. University of Lagos, Lagos: B.Sc. Physiology, 1997
  3. University of Lagos, Lagos: M.Sc. Physiology, 2000
  4. University of Lagos, Lagos: Ph.D. Physiology, 2010

Previous Employments With Dates:

  1. Graduate Assistant, March 1999 – September, 2000
  2. Assistant Lecturer, October 2000 – September 2001
  3. Lecturer II, October 2001 – September 2004
  4. Lecturer I, October 2004 – September 2008
  5. Senior Lecturer, October 2008 – Date

Duties Performed:

  1. Graduate Assistant:

Coordinating and organizing Physiology practical for the students of the Faculties of Medical Sciences (2nd and 3rd year medical students), Dentistry (2nd and 3rd year dental students), Health Sciences and Technology (Medical laboratory sciences, Medical rehabilitation, Medical radiography and Nursing sciences).

  1. Assistant Lecturer:

Teaching and examining students of the Faculties of Medical Sciences (2nd and 3rd year medical students), Dentistry (2nd and 3rd year dental students), Health Sciences and Technology (Medical laboratory sciences, Medical rehabilitation, Medical radiography and Nursing sciences students) Gastrointestinal Physiology, Neurophysiology and Endocrine and Reproductive Physiology.

Coordinating and organizing Physiology practical for these groups of students.

  1. Lecturer II:

Same as for Assistant Lecturer

  1. Lecturer I:

Teaching and examining students of the Faculties of Medical Sciences (2nd and 3rd year medical students), Dentistry (2nd and 3rd year dental students), Health Sciences and Technology (Medical laboratory sciences, Medical rehabilitation, Medical radiography and Nursing sciences students) Gastrointestinal Physiology.

Organizing Physiology practical, in these areas, for these groups of students.

  1. Senior Lecturer:

Teaching and examining students of the Faculties of Medical Sciences (2nd and 3rd year medical students), Dentistry (2nd and 3rd year dental students), Health Sciences and Technology (Medical laboratory sciences, Medical rehabilitation, Medical radiography and Nursing sciences students) in Excitable Tissues.

Teaching and examining Postgraduate Physiology Students in Cell and Excitable Tissues, Gastrointestinal Physiology, Reproductive Physiology, Research Methodology and Laboratory Techniques in Physiology

Organizing Physiology practical, in these areas, for these groups of students.

Supervised Eight (8) M.Sc. Projects and one (1) Ph.D thesis and currently supervising four (4) M.Sc students and two (2) Ph.D students.

Other Duties Performed:

  1. Member, Disciplinary committee, Faculty of Medical Sciences, College of Medicine, University of Nigeria, Enugu Campus, Enugu.                                   2004-2010.
  2. Member, Examination committee, Department of Physiology, College of Medicine, University of Nigeria, Enugu Campus, Enugu.                                   2005-2010.
  3. Member, Postgraduate program committee, Department of Physiology, College of Medicine, University of Nigeria, Enugu Campus, Enugu.                         2007-2010.
  4. Chairman, Examination committee, Department of Physiology, College of Medicine, University of Nigeria, Enugu Campus, Enugu.                         2010-2011.
  5. Coordinator, Postgraduate program, Department of Physiology, College of Medicine, University of Nigeria, Enugu Campus, Enugu.                                    2010-2012.
  6. Acting Head, Department of Physiology, College of Medicine, University of Nigeria, Enugu Campus, Enugu.             01/08/ 2012-31/07/2013.
  7. Editor In Chief, Nigerian Journal of Experimental and Clinical Biosciences                                                                                   2012-Date.

 

Attendance at Conferences

 

Conference Title                                                                     Date                Place

 

22nd Annual Scientific Conference of Physiological              2002                Ibadan

Society of Nigeria

 

23rd Annual Scientific Conference of Physiological               2003                Lagos

Society of Nigeria

 

25th Annual Scientific Conference of Physiological               2005                Benin

Society of Nigeria

 

26th Annual Scientific Conference of Physiological               2006                PH

Society of Nigeria

 

28th Annual Scientific Conference of Physiological               2008                Ilorin

Society of Nigeria

 

30th Annual Scientific Conference of Physiological               2010                Ikeja

Society of Nigeria

 

 

 

Workshop/Training                                           Date                         Place

 

International Brain Research Organization     July 18-26, 2007   University of Lagos

(IBRO) Neuroscience Course

 

Medical Education Partnership Initiative       July 11-12, 2013   University of Ibadan

Nigeria (MEPIN) organized Training on

Computer assisted practical exercise in

Physiological Sciences

 

Medical Education Partnership Initiative       July 30-31, 2013     University of Nigeria

Nigeria (MEPIN) Training of Trainers on

Teaching by Case Based Methods

 

Professional Review of Papers for Reputable Journals

 

Title of Papers Reviewed                                Journal                         Date

 

Chronic administration of aqueous                 Pharmaceutical            20/5/2011

Extract of Hibiscus sabdariffa alone               Biology

and in combination with valsartan

attenuates hypertension in 2-kidney

1-clip Hypertensive rats: A comparative

study with valsartan.

 

Anticancer activity of flavonol and                Pharmaceutical            3/7/2012

flavan-3-ols rich extract from Croton             Biology

celtidifolius Baill latex

 

Exposure of pregnant rats to genistein            Pharmaceutical            31/5/2014

alters amniotic fluid, placental, and                Biology

plasma, leptin level; maternal thyroid

hormones, and c-reactive protein

 

Referees:

  1. Prof R.O NNELI,

Dept Of Physiology,

Faculty of Basic Medical Sciences,

Federal University, Ndufu-Alike, Ikwo,

Ebonyi State, Nigeria.

profronneli_2007@yahoo.com

 

  1. Prof E. N. SHU,

Dept Of Pharmacology and Therapeutics,

College of Medicine, University of Nigeria,

Enugu Campus, Enugu,

Nigeria.

enshu1@yahoo.com

 

  1. Prof I. E. EZEAGU,

Dept Of Medical Biochemistry,

College of Medicine, University of Nigeria,

Enugu Campus, Enugu,

Nigeria.

ikezeagu@yahoo.co.uk

 

 

Publications

Research Articles

  1. ADEGOKE, O. A. and IYARE, E. E. (1999): Metabolic Action Of Sex Steroids: The Effects Of Testosterone and Progestins On Hepatic Glycogen Deposition. Nigerian Quarterly Journal of Hospital Medicine 9 (1) 71-73.

 

  1. ADEGOKE, O. A.; IYARE, E. E. and Gbenebitse S. O. (2003): Fasting plasma glucose and cholesterol levels in pregnant Nigerian women. Nigeria Postgraduate Medical Journal. 10 (1): 32-36.

 

  1. IYARE, E. E. and IYARE, F. E. (2006): Lactational exposure to an aqueous extract of Hibiscus Sabdariffa (Hs) accelerates offspring’s early postnatal growth in Sprague-Dawley rats. Journal of Experimental and Clinical Anatomy. 5(1): 6-9.

 

  1. IYARE, E. E. and IYARE, F. E. (2006): Effect of in utero exposure to an aqueous extract of Hibiscus sabdariffa on offspring’s postnatal growth in Sprague-Dawley rats. Nigerian Journal of Health and Biomedical Sciences. 5 (1): 27-30.

 

  1. IYARE, E. E. and IYARE, F. E. (2006): The effect of an aqueous extract of Hibiscus sabdariffa on gestational weight gain, pregnancy outcome and postpartum weight retention in Sprague-Dawley (SD) rats. Nigerian Journal of Health and Biomedical Sciences. 5 (2): 26-29.

 

  1. IYARE, E. E. and IYARE, F. E. (2007): Maternal consumption of aqueous extract of Hibiscus sabdariffa during pregnancy attenuates pregnancy weight gain and postpartum weight loss. African Journal of Biomedical Research 10: 257-261.

 

  1. IYARE, E. E. and ADEGOKE, O. A. (2008): Mechanism of the delayed puberty onset in offspring of rats that consumed aqueous extract of hibiscus sabdariffa during pregnancy. Nigeria Journal of Physiological Sciences 23 (1-2): 71-77.

 

  1. IYARE, E. E. and ADEGOKE, O. A. (2008): Maternal consumption of an aqueous extract of Hibiscus sabdariffa during lactation accelerates postnatal weight and delays onset of puberty in female offspring. Nigeria Journal of Physiological Sciences 23 (1-2): 89-94.

 

  1. IYARE, E. E. and ADEGOKE, O. A. (2008): Body mass index at onset of puberty in rats exposed to aqueous extract of Hibiscus sabdariffa in utero. African Journal of Biomedical Research 11: 203-208.

 

  1. IYARE, E. E. and IYARE, F. E. (2008): Effect of prenatal and postnatal exposure to an aqueous extract of Hibiscus sabdariffa on postnatal growth in Sprague-Dawley rats. Pakistan Journal of Nutrition 7 (2): 255-257.

 

  1. IYARE, E. E. and ADEGOKE, O. A. (2008): Postnatal weight gain and onset of puberty in rats exposed to aqueous extract of Hibiscus sabdariffa in utero. Pakistan Journal of Nutrition 7 (1): 98-101.

 

  1. NWAGHA, U. I., EJEZIE, F. E. and IYARE, E. E. (2009): Evaluation of serum uric acid levels in normal pregnant Nigerian women. Nigerian Journal of Clinical Practice. 12 (1) 83-86.

 

  1. IYARE, E. E. and NWAGHA, U. I. (2009): Postweaning Consumption of Aqueous Extract of Hibiscus sabdariffa May Predispose Rats to Obesity. Pakistan Journal of Nutrition 8 (11): 1760-1765. Journal of Phytology 2010, 2(2): 01–09

 

  1. IYARE, F. E., IYARE, E. E. and ADEGOKE, O. A. (2009): Morphologic changes in the utero-ovarian tissues of the offspring of rats that consumed aqueous extract of Hibiscus sabdariffa calyx during lactation. Journal of Experimental and Clinical Anatomy 8 (2): 10-15.

 

  1. IYARE, E. E. and NWAGHA, U. I. (2009): Delayed puberty onset in rats that consumed aqueous extract of Hibiscus sabdariffa during the juvenile-pubertal period. Pakistan Journal of Biological Sciences 12 (23): 1505-1510.

 

  1. IYARE, E. E., ADEGOKE, O. A. and NWAGHA, U. I. (2010): Mechanism of delayed puberty in rats whose mothers consumed Hibiscus sabdariffa during lactation. Pharmaceutical Biology 48 (10): 1170-1176.

 

  1. IYARE, E. E., ADEGOKE, O. A. and NWAGHA, U. I. (2010): Mechanism of the decreased food consumption and weight gain in rats following consumption of aqueous extract of the calyx of Hibiscus sabdariffa during pregnancy. Asia Pacific Journal of Tropical Medicine 3(3): 185-188.

 

  1. NWAGHA, U. I., OKEJI, N., CLEMS-ANUNWA, O., EJEZIE, F. E., NWAGHA, T. U. and IYARE, E. E. (2010): The role of some micronutrients (Eldervit-12 in the management of anaemic pregnant Nigerian women: A preliminary report. Tropical Journal of Obstetrics and Gynaecology. Tropical Journal of Obstetrics and Gynaecology. 27 (2): 34-39.

 

  1. IYARE, E. E. and ADEGOKE, O. A. (2011): Effect of lactational exposure to an aqueous extract of Hibiscus sabdariffa on body mass index at onset of puberty in female Sprague-Dawley rats. Pakistan Journal of Nutrition 10 (4): 360-364.

 

  1. IYARE, E. E. and ADEGOKE, O. A. (2011): Gestational outcome in rats that consumed aqueous extract of Hibiscus sabdariffa during pregnancy. Pakistan Journal of Nutrition 10 (4): 350-354.
  2. NWAGHA, U. I., IYARE, E. E., EJEZIE, F. E., OGBODO, S. O., DIM, C. C.and ANYAEHIE, B. U. (2012): Parity related changes in obesity and some antioxidant vitamins in non-pregnant women of South Eastern Nigeria. Nigerian Journal of Clinical Practice 15 (4): 380-384.

 

  1. OKEREKE, C., OKEKE, T. C., ANYAEHIE, B. U., NWAGHA, U.I., IYARE, E. E., NWOGU-IKOJO, E., and ORIZU, I. A. (2012): The effect of gravidity on anthropometric indices of pregnant women in Enugu, South East Nigeria. African Journal Biomedical Research. 15; 165-170.

 

  1. IYIDOBI, E. C., ANYAEHIE, U. S. B., IGWEH, J. C. and IYARE, E. E. (2013): Leukocyte profile of adult Nigerian subjects with acute musculoskeletal trauma. Nigerian Journal of Medicine 22(1): 32-36.

 

  1. NWAGHA, U. I., IYARE, E. E., OGBODO, S. O., AGU, P. U., OLUBOBOKUN, T. H., EZEONU, P. O. and ONYEBUCHI, A. K. (2013): Parity-related changes in body weight may influence the zinc and copper status of urban pregnant women: a report from south eastern Nigeria. Journal of Basic and Clinical Reproductive Sciences 2(1): 32-37.

 

  1. OLUBOBOKUN, T. H., ALUKO, E. O., IYARE, E. E. and ANYAEHIE, U. B. (2013): Dioscorea alata reduces body weight by reducing food intake and fasting blood glucose level. British Journal of Medicine and Medical Research 3(4): 1871-1880.

 

  1. NUBILA, T., UKAEJIOFO, E. O., NUBILA, N. I., IYARE, E. E., SHU, E. N., CHIJIOKE, C.P. and IBOK, I. F. (2013): Subacute effects of Methanolic crude leaf extract of Gnetum africanum on the haematological profile in albino Wistar rats. International Journal of Aromatic Plants 3 (2): 220 -225.

 

  1. OLUBOBOKUN, T. H., ALUKO, E. O., IYARE, E. E., ANYAEHIE, U. B. and ATANG, D. E. (2013): Ipomoea batatas extract reduces food intake, fasting blood glucose levels and body weight. European Journal of Medicinal Plants 3(4): 530-539.

 

  1. SORONNADI, C. N., ANYEHIE, B. U., IYARE, E. E., NEBOH, E. E., ODIEGWU, C. N. C. and ODURUKWE, O. (2013): Oral supplementation of vitamin C reverses haemostatic dysfunction in chronic smokers. Biomedical Research 24 (4): 458-462.

 

  1. NUBILA, T., UKAEJIOFO, E. O., NUBILA, N. I., SHU, E. N., OKWUOSA, C. N., UKAEJIOFO, A. C., IYARE, E. E. and OGBUTA, O. I. (2013): Effects of Methanolic seed extract of Telfairia occidentalis on blood coagulation in albino rats. Nigerian Journal of Experimental and Clinical Biosciences 1 (1 and 2): 10-13.

 

  1. NUBILA, T., UKAEJIOFO, E. O., NUBILA, N. I., IYARE, E. E., CHIJIOKE, C. P., UKAEJIOFO, A. C., SHUNEBA, I. L. and AGUNBAH, S. J. (2013): Methanolic crude leaf extract of Ocimum gratissimum reverses phenylhydrazine-induced anemia in albino Wistar rats. Nigerian Journal of Experimental and Clinical Biosciences 1 (1 and 2): 23-27.

 

  1. NUBILA, T., UKAEJIOFO, E. O., NUBILA, N. I., OKWUOSA, C. N., CHIJIOKE, C. P., SHU, E. N.and IYARE, E. E. (2013): Subacute effects of crude Methanolic leaf extract of Mucuna flagellipes (Vogel ex Hook) on haematological profile and haematinic activities in albino Wistar rats. International Journal of Medicinal and Aromatic Plants 3 (4): 452-458.

 

  1. OKEREKE, C. E., ANYAEHIE, B. U., DIM, C. C., IYARE, E. and NWAGHA, U. I. (2013): Evaluation of some Anthropometric Indices for the Diagnosis of Obesity in Pregnancy in Nigeria: A cross-sectional study. African Health Sciences 13(4): 1034-1040.

 

  1. NUBILA, T., UKAEJIOFO, E. O., IKE, S. O., SHU, E. N., NUBILA, N. I., CHIJIOKE, C. P., UKAEJIOFO, A. C., IYARE, E. E., OKWUOSA, C. U. and OKWUOWULU, O. V. (2014): Predisposing factors associated with uncomplicated type-2 diabetes among adults in a diabetic clinic, Enugu state, Nigeria. Transactions of the Royal Society of Tropical Medicine and Hygiene 108 (4): 206-212.

 

  1. IYARE, E. E. and OBAJI, N. N. (2014): Effects of aqueous leaf extract of Azadirachta indica on some haematological parameters and blood glucose level in female rats. Nigerian Journal of Experimental and Clinical Biosciences 2 (1): 54-58.

 

  1. NWAGHA, U., IYARE, E., ANYAEHIE, U., ONYEDUM, C., OKEREKE, C., AJUZIEOGU, O., AMUCHEAZI, A., OLUBOBOKUN, T., AGU, P., IGWEH, J. and OGUANUO, T. (2014): Forced expiratory volume in 6 s FEV6) and FEV1 /FEV6 values as a viable alternative for forced vital capacity (FVC) and FEV1/FVC values during pregnancy in South East Nigeria: A preliminary study. Annals of Medical and Health Sciences Research 4:516-21.

 

  1. OLUBOBOKUN, T. H., ALUKO, E. O., IYARE, E. E., ANYAEHIE, U., OLATUNBOSUN, E. D. and AIZENABOR, G.I. (2014): Aqueous extract of Ipomoea batatas reduces food intake in male wistar rats: A pilot study. Ann Med Health Sci Res 4:647-9.

 

  1. ANYAEHIE, U. B., OKEKE, T., NWAGHA, U., ORIZU, I., IYARE, E., DIM, C. and OKAFOR, C. (2014): Impact of some low-cost interventions on students performance in a Nigerian medical school. Nigerian Journal of Clinical Practice 17(5): 555-558.

 

  1. IYARE, E. E., OBAJI, N. N., EZEH, C. O., NUBILA, T. and ORIZU, I. A. (2014): Effect of Consumption of aqueous extract of Azadirachta indica during pregnancy on pregnancy outcome in rats. Pensee Journal 76 (9): 308-316.

 

 

Books

  1. IYARE, E. E. (2009): Gastrointestinal Physiology. In: Fundamental Multiple Choice Questions In Medical Physiology With Answers And Comments. Edited by Dr. Uchenna Ifeanyi Nwagha. Published by Ezu Books Ltd, Enugu, Nigeria. Chapter 6, pages 83-104.

 

  1. IGWEH, J. C., UDE, J. F., NWAGHA, U. I., NWACHUKWU, D. C., ORIZU, I. A., IYARE, E. E. and NWEKE, M. L. (2005): Experimental Physiology for Medical and Allied students. ISBN 978-36988-O-X. Chenglo press, Enugu, Nigeria.

 

 

Thesis/Projects

  1. Impact Of Hibiscus Sabdariffa Calyx Aqueous Extract Consumption By Pregnant And Lactating Sprague-Dawley Rats On Pregnancy Outcome And Postnatal Development. Ph.D thesis, 2010, Dept of Physiology, College of Medicine, University of Lagos, Nigeria.

 

  1. Fasting Plasma Glucose And Cholesterol Levels In Pregnant Nigerian Women. M.Sc. Dissertation, 2000, Dept of Physiology, College of Medicine, University of Lagos, Nigeria.

 

  1. Assay Of Testosterone And Progesterone For Glucocorticoid Or Antiglucocorticoid Activities In Vivo. B.Sc. Project, 1997, Dept of Physiology, College of Medicine, University of Lagos, Nigeria.

 

 

research line

IYARE, FESTUS EHIGIATOR

ASSOCIATE PROFESSOR OF PATHOLOGY

DEPARTMENT OF PATHOLOGY

EBONYI STATE UNIVERSITY/FEDERAL TEACHING HOSPITAL, ABAKALIKI

PMB 53/PMB 102, ABAKALIKI 480001

EBONYI STATE, NIGERIA

 

  1. PERMANENT HOME ADDRESS: 113, EKEHUAN ROAD,

PO BOX 6466, BENIN-CITY

EDO STATE, NIGERIA

  1. EMAIL:                                                                                                festus_iyare@yahoo.com
  2. 234-803-7170172
  3. DATE OF BIRTH:                                                                                 5TH JUNE 1958
  4. GENDER/NATIONALITY:                                                                   M/NIGERIAN
  5. MARITAL STATUS/NUMBER OF CHILDREN:                                  MARRIED/4

 

 

1.      EDUCATIONAL BACKGROUND:

 

       TYPE                           DATE                       INSTITUTIONS                               QUALIFICATIONS/DATE

 

  • PRIMARY                 1966-1971               NBC PRY. SCH. B/C                                 FLSC/1971
  • SECONDARY             1972-1976               ICC, BENIN-CIYT                                     WASC/1976
  • POST SECONDARY   1976-1977              EDO COLLEGE, B/C                                 ADVANCED LEVEL
  • TERTIARY                 1977-1978             UNIVERSITY OF LAGOS                           PRELIM MED./1978
  • GRADUATE               1978-1983             COLLEGE OF MEDICINE(UNILAG)          MBBS/1983
  • 1990-1995             NPMCN/LUTH                                           FMCPath./1995

.                                                                                                                                                                                    .

 

  1. WORK EXPERIENCE:
  • Housemanship:            In specialist Hospital, Benin City, Nigeria (Nov. 1983 – Nov. 1984)

Job Description:           Rotate through the four major departments of 3 Month duration each that is, Department of MEDICINE, SURGERY, OBSTETRICS & GYNAECOLOGY and PAEDIATRICS. This Period also include posting to the Casualty Sections of the relevant Departments.

 

  • National Youth Service     In Birnin-Kudu General Hospital, Kano, Kano State Nov. 1984 to Nov. 1985

Job Description:         Worked as Senior House Officer and the first point of contact with Medical Doctor by almost all patients that come to hospital. I was in charge of the management of most patients seen by me Including Medical, Surgical (including surgeries) Obstetric, Gynaecological and Paediatric problems and Emergencies

  • Medical Officer: In charge of St. Mary’s Hospital, Okpoga (Catholic Diocese of Makurdi), Benue State November 1985 to August 1987.
  • Senior Medical Officer:   In charge of St. Damian’s Hospital, Okporo (Catholic Diocese of Orlu), Imo State between September, 1987 and January, 1990.

Job Description:                       I was in charge of all Medical, Surgical, Obstetric & Gynaecoogy and Paediatric problems of patients including minor and or major surgical Procedures like Spelenectomies, Intestinal resection and anastomosis, Cesaerian Sections, Hystrectomies, Herniorrhaphies,Appendectomies where necessary. This also includes some Administrative responsibility for the hospital regarding medical matters. These Hospitals are situated in the rural and peri-urban areas of the respective states of Nigeria.

 

2a.       Registrar:                                                         In Morbid Anatomy/Histopathology of the

Department of Morbid Anatomy of Lagos

University Teaching Hospital between February,

1990 and June 1992.

Job Description:

  • To perform and interpret gross and microscopic findings on almost all autopsies including difficult cases.
  • To interpret and report the majority of cytology cases.
  • To assist in the training of first year residents and Medical students.
  • To present material at departmental and hospital rounds including clinicopathologic conferences.
  • Interpretative autopsy demonstration to medical students, Clinicians and Surgeons in relevant cases.
  • Organisation of resident seminars, journals clubs, etc
  • To undertake rotations of 3 months each and participate actively in the routine and other works of the other branches of pathology; viz: Microbiology and Parasitololgy,Chemical Pathology and Haematology and Blood Transfusion.

 

 

2b.      SENIOR REGISTRAR                                       in Morbid Anatomy/Histopathology Department of

Lagos University Teaching Hospital

Job Description:                    

  • In addition to the duties of Registrar, I am to perform the following duties among many others:
  • To perform and interpret gross and microscopic findings on all autopsies especially difficult and special cases involving special techniques.
  • To perform in the training of first year, second year residents, and medical students.
  • To interpret and report all cytology cases.
  • To conduct research and present papers/materials for publications in journals and scientific conferences.

 

2c.       CHIEF REDIDENT:                       In Morbid Anatomy/Histopathology Department of

Lagos University Teaching Hospital

Job Description:                    

  • In addition to the duties as Senior Registrar, I am to oversee the smooth running of the various routine duties of each Resident and other duties assigned by the Head of Department

2d.       CONSULTANT PATHOLOGIST/CHIEF MEDICAL OFFICER

St. Damian’s Hospital, Okporo-Orlu, Imo State May 1995 till 2004

         Job Description

*             Supervise other Medical Doctors

*          Organise and supervise the Medical/Surgical; Services

*          Organise and supervise the Maternity & Child welfare services

*          Organise and Supervise the Primary health care Home/Health. Outpost visiting services

*          Supervise Laboratory services

*          Supervises the ultrasonography/Imaging Unit

*          Report on all Biopsy/Cytology Specimens.

*          Interpret all Autopsies.

*          Organise and supervise the mortuary and funeral services unit

*          Organise and Supervise the Cancer Screening Programme of the Diocesan Health Services.

*          Other duties assigned by the Diocesan Health Management Committee

 

2e.       CHIEF CONSULTANT PATHOLOGIST/ASSOCIATE PROFESSOR OF PATHOLOGY

Federal Teaching Hospital/Ebonyi State University, 2005 – /2011 – till date

Job description

*           Organize and provide histopathology services

*            Organize and provide cytology services

*           Train resident doctors in pathology

*           Teach medical, nursing science, medical laboratory science, and anatomy students’ pathology

*           Research and administrative duties

  1.          MEMBERSHIP OF PROFESSIONAL BODIES:
  2. Nigerian Medical Association
  3. Fellow of National Postgraduate Medical College of Nigeria
  4. Association of Pathologists of Nigeria.
  5. Medical and Dental Consultants of Nigeria(MDCAN)
  6. Fellow international college of surgeons
  7. West African division of international academy of pathology

 

  1. PREVIOUS POPSITIONS HELD:
  2. i)     Director of Pathology Services and Cancer Screening Center at St. Damian’s Hospital, Okporo-Orlu, Imo State. 1995-2001
  3. ii)   Head of Department of Pathology, Abia State University, Uturu, Abia State, Jan. 1996-Jan – Jan. 2001

iii)   Lecturer in Anatomic Pathology/Forensic Medicine, Abia State University Jan. 1996 – Jan. 2001

  1. iv)   Consultant Histopathologist to the Abia State University Teaching Hospital Aba Jan. 1996 – Jan. 2001
  2. v)   Visiting Senior Lecturer in Morbid Anatomy/Histopathology, Ebonyi State University Jan. 2000-2011
  3. vi)   Visiting Honorary Consultant Pathologist to Ebonyi State University Teaching Hosp. Jan. 2000-2011

vii) Senior Consultant Pathologist, Federal Medical centre, Abakaliki April 2001 – March 2005

viii) Chief consultant Pathologist, Federal Medical Centre, Abakaliki April 2005 – September 2011

  1. ix)   Head of Dept. Morbid Anatomy/Histopathology, EBSU, 2000-2001, 2007-2008, 2013-Aug. 2014
  2. x)   Head of Dept. Haematology & Blood transfusion, EBSU, 2001-2002
  3. xi)   Head of Dept. Chemical Pathology, EBSU, 2011-2013

xii) Coordinator of Residency Training Program, FETHA, 2012 – July 2014

xiii) Sub Dean, Faculty of Clinical Medicine, CHS, EBSU, 2012 – July 2014

 

 

 

5.      CURRENT POSITIONS:

 

*       Examiner in Faculty of Pathology, NPMCN, 2005 – till date

*       Chief Consultant Pathologist, FETHA, October, 2011 – till date

*       Associate Professor of Pathology, EBSU, October, 2011 – till date

*       Member Learning Resources Committee of NPMCN, 2011 – till date

*       Chairman, Faculty Curriculum Committee, FCM, EBSU, 2012 – till date

*       Head of Dept. Pathology, EBSU, 1st August, 2014 – till date

  1. OTHER ACTIVITIES:

*     President,Federated ( EBSUTH) Staff Credit & Thrift Cooperative Society Ltd. 2011-till date

 

  1. SELECTED WORKSHOPS AND COURSES:

*     European Advanced Postgraduate Course in Classical and Molecular Cytogenetics, Nimes, France, 3rd – 11th March 2014

*     The Contribution of Anatomic Pathology to health of women and children, Harvard Medical School, 4th – 8th November, 2013

*     Advanced Research Methodology Course, National Postgraduate Medical College of Nigeria, 4th -6th July 2012

*     Human Subject Protection, Protocol Review and community engagement in research, Abakaliki, 25th – @8th May, 2011

*     Train the Trainers Workshop in Modern Docimology Methods, 22nd – 26th September 2010

 

 

REFEREES:

 

  1. Prof. C. O. O Chukwu            Former, Federal Minister of Health

Federal Ministry of Health

Abuja, Nigeria

buchichukwu@yahoo.com

234-08037621816

234-08036660605

 

  1. Prof. C.A. Attah College of Health Sciences

Ebonyi State University, PMB 077

Abakaliki, 480001

Ebonyi State – Nigeria

cattahprof@yahoo.com

234-8034101232

 

  1. Prof. E. U. Ajuluchuku                                 College of Health Sciences

Ebonyi State University

Abakaliki, 480001

Ebonyi State, Nigeria

estherajuluchuku@yahoo.com

234-8033944611

LIST OF PUBLICATIONS

 

  1. Iyare F. E. Endometrial biopsy and histopathological diagnosis: A 10 year review. JOMIP Vol. 1 Nov 2000: 13

 

  1. Iyare F. E. Advanced Abdominal Pregnancies at St. Damian’s Hospital, Orlu, Nigeria. Journal of Health and Visual Sciences (3), 2001: 19-23.

 

  1. Iyare F. E. Breast Cancers in Orlu, Nigeria. Journal of Health and Visual Sciences (3), 2001: 31-35.

 

  1. Iyare F. E. Diseases of the male breast. Journal of Health and Visual Sciences (3), 2001: 36-38.

 

  1. Iyare F. E. Patterns of cancers in Orlu, Nigeria. Journal of Health and Visual Sciences (3), 2001:

 

  1. Iyare F. E. Tumours of the breast in Orlu, Nigeria. Journal of Health and Visual Sciences (4), 2002:

 

  1. Iyare F. E., Ikerionwu S.E., Emedike S.O.C. Leiomyomatosis peritonealis disseminate in a Nigerian male. Journal of Health and Visual Sciences (5), 2003: 71-75.

 

  1. Iyare F. E. Menstruation and its associated perculiarities in Nigerian Girls. Journal of Health and Visual Sciences (6), 2004: 1-6.

 

  1. Amadife M.U, Iyare F.E. The need for high index of suspicion in early diagnosis of typhoid fever in young children. Nigerian Journal of Medicine, 2006

 

  1. Onuoha C.E.O, Iyare F.E. Dicephalic-dipus: A case report. West African Journal of Medicine 25 (2); 2006: 161-163.

 

  1. Ajuluchuku E.U, Imo A.O.C, Iyare F.E. Unusual presentation of greater curvature omental cyst. Ebonyi Medical Journal 5 (1); 2006: 28-31

 

  1. Iyare E.E, Iyare F.E. Effect of inutero exposure to an aqueous extract of hibiscus sabdariffa on offspring’s postnatal growth in Sprague-Dawley rats. Nigerian Journal of Health and Biomedical Sciences 5 (1); 2006: 27-30

 

  1. Iyare E.E, Iyare F.E. Lactational exposure to an aqueous extract of hibiscus sabdariffa (HS) accelerates offspring’s early postnatal growth in Sprague-Dawley rats. J. Expt. & Clin. Anat. 5(1); 2006: 6-9.

 

  1. Iyare E.E, Iyare F.E. The Effect of an aqueous extract of hibiscus sabdariffa on gestational weight gain, pregnancy outcome and postpartum weight retention in Sprague-Dawley (SD) rats. Nigerian Journal of Health and Biomedical Sciences 5 (2); 2006: 26-29.

 

  1. Uneke C.J, Sunday-Adeoye I, Iyare F.E, Uguja E.I, Duhlinska D.D. Impact of maternal plasmodium falciparum malaria and haematological parameters on pregnancy and its outcome in southeastern Nigeria. J Vector Borne Dis 44; 2007: 285-290.

 

  1. Iyare F.E. Mixed mesodermal tumour of the ovary coexisting with adenocarcinoma of the ileum in a postmenopausal Nigerian woman. Ebonyi Medical Journal 6 (2); 2007: 114-117

 

  1. Iyare E.E, Iyare F.E. Maternal consumption of aqueous extract of hibiscus sabdariffa during pregnancy attenuates pregnancy weight gain and postpartum weight loss. Afr. J. Biomed. Res. 10; 2007: 257-261

 

  1. Iyare F.E. Immunohistochemical characteristics of breast cancers in south east Nigeria. Ebonyi Medical Journal 6 (1); 2007: 9-12.

 

  1. Uneke C.J, Iyare F.E, Adeoye I.S, Ajayi J.A. Evaluation of maternal malaria at childbirth using rapid diagnostic test and its relationship with birth weight and fetal hemoglobin levels in Nigeria. The Internet Journal of Gynecology and Obstetrics 10 (1); 2008.

 

  1. Iyare E.E, Iyare F.E. The Effect of prenatal and postnatal exposure to an aqueous extract of hibiscus sabdariffa (HS) on postnatal growth in Sprague-Dawley rats. Pakistan Journal of Nutrition 7 (2); 2008: 255-257.

 

  1. Uneke C.J, Iyare F.E, Sunday-Adeoye I, Ajayi J.A. An assessment of the impact of placental plasmodium falciparum malaria on perinatal outcome in Nigeria. The Internet Journal of Parasitic Diseases 3 (2); 2008.

 

  1. Uneke C.J, Iyare F.E, Oke P, Duhlinska D.D. Assessment of malaria in pregnancy using rapid diagnostic tests and its association with HIV infection and hematological parameters in south-eastern Nigeria. Haematologica. 93 (1); 2008: 143-144.

 

  1. Iyare F.E. Diseases of the prostate among Igbos of southeastern Nigeria. Ebonyi Medical Journal 7 (1&2); 2008: 8-13.

 

  1. Huo D, Ikpatt F, Khramtsov A, Dangou JM, Nanda R, Dignam J, Zhang B, Grushko T, Zhang C, Oluwasola O, Malaka D, Malami S, Odetude A, Adeoye AO, Iyare FE, Falusi A, Perou CM, Olopade OI. Population differences in breast cancer: Survey in indigenous African women reveals overrepresentation of triple negative breast cancer. J Clin Oncol. 27(27); 2009: 4515-4521.

 

  1. Iyare F.E, Iyare E.E, Adegoke O.A. Morphologic changes in the utero-ovarian tissues of the offsprings of rats exposed to aqueous extract of hibiscus sabdariffa during lactation. J.Expt. & Clin. Anat. 8(2): 10-15

 

  1. Agwu UM, Umeora OUJ, Ogbonnaya LU, Iyare FE, Obuna JA, UMahi G, Egwuatu VE. Fetal Umbilical Cord length and associated Intrapatrum complications in a tertiary institution, Southeast Nigeria, Ebonyi Medical Journal. 9(2); 2010: 112-118

 

PUBLISHED BOOKS

 

  1. That We May Live and Be Free (A patho-scriptural peep into the death of Jesus Christ on the cross), 1999, Charismatic Forum Publications Ltd. Owerri

 

  1. Pathological Sciences: MCQ guide to medical students, 1999, K.K Integrated Systems, Owerri.

 

  1. Pathological Sciences: Review Objective Tests for Medical Students, 2005, Bills Prints & Publishers, Amawbia, Anambra State.

 

  1. The Medical Witness, 2008, Larry & Caleb, a Copycraft International company, Abakaliki.

 

 

research line                                       CURRICULUM VITAE

CHARLES OGBONNA EZEH

 

Department of Medical Biochemistry, Faculty of Medical Sciences, College of Medicine,   University of Nigeria, Enugu Campus, Enugu, Nigeria.

 

 

E- mail: charlesezeh@yahoo.com,  charles.ezeh@unn.edu.ng

Phone: +234(0)803709312, +234[0]8163772395

 

PERSONAL DATA

Sex:                                 Male

Current Position:         Lecturer I

State of Origin:             Enugu State

Date of Birth:               25th August, 1972

Local Govt. Area:         Uzo-Uwani

 

EDUCATION

University of Port Harcourt, Port Harcourt (Ph.D) Biochemistry- 2009

University of Port Harcourt, Port Harcourt (M.Sc.) Biochemistry- 2005

University of Nigeria, Nsukka Campus (B.Sc.) (Hons) Biochemistry- 1997

St. Teresa’s College Nsukka.(Senior School Certificate/G.C.E.)- 1990

 

THESIS/DISSERTATION

  1. Applications of some plant peroxidases in Bread Baking. Pulp and Paper Processing.-Ph.D Dessertation

 

  1. Comparative study of some properties of peroxidase from black beans (Phaseolus vulgaris and Pigeon pea (Cajanus cajan).-M.Sc. Thesis

 

  1. Some Properties of Sorgum and Rubber seed Peroxidases.-B.Sc.

 

PUBLICATIONS

  1. Obiekezie  SO,  Ezeh  CO, Okhiai O,  Verla  AW (2007)

Preliminary Investigations on the phytochemical and antibacterial activities of inyi plant leaves (Erthrophleum suaveloens) Int. J. Biotechnol & Allied Sc 2(3): 272-274.

 

  1. Obiekezie, S. O. Eze, C. O., Ibegbulam, G.O. and Verla, A. W (2007)

Seasonal variation of levels of toxic/Heavy metal of Bilante rock mining pit water Ishiagu, Ebonyi State(2007). Int  J  Biotechnol & Allied Sc 2(3) :  297-299.

 

  1. Ezeh CO, Ubenyi  SM,  Nweke ML. (2009)  Antisickling effect of Aloe vera extract on sodium metabisulphite induced sickling on human erythrocytes Int. J. Biotechnol& Allied Sc 4(1) 288-292.

 

  1. Ezeh CO, Ubenyi  SM,  Nweke ML. (2009)  Effects of co-administration of chloramphenicol and garcinia Kola extract on liver and kidney functions of whistar rats. Int. J. Biotechnol. And Allied Sc 4(1): 233-240.

 

  1. Ezeh CO, Nweke ML, Ubenyi  SM,  (2009)  Some changes ib biochemical parameters of kidney and liver functions in whistar rats co-administered with tarivid and garcinia kola extract Int. J. Biotechnol &Allied Sc 4(2): 193-199.

 

  1. Ezeh CO, Nweke ML, Ubenyi  SM, (2009) Changes in some biochemical indices of liver and kidney functions of whistar rats co-administered with garcinia kola extract and halofantrine(antimalarial) Int. J. Biotechnol & Allied Sc 4(1): 87-94

 

  1. Ezeh CO, Akinwale, OP  Shan L, Zhang T  Zheng Q, Chitsulo L, Wei H (2012) Urinary schistosomiasis in Nigeria: A 50 years review of prevalence, distribution and disease burden-in Press

 

  1. Nweze EI, Ezute S, Emeka Nweze CC, Ogbonna CC, Eze C.O. (2012)

Bacteria etiological agents causing respiratory tract infections in children

and their resistance patterns to a panel of ten antibiotics Asian Pacific Journal

of Tropical Disease, 18-23.

 

BOOKS

  1. Ezeh, C.O. and Ude, C. M (2006) Essentials of Enzymology.  JTC Publishers ISBN: 978-35036-3-4

 

  1. Ezeh, C.O. Achikanu, C.E and Amadife, (2006)  Introductory Biochemistry . His Glory Publications ISBN: 978-37896-7-8

 

  1. Ezeh, C. O.(2006 Revised 2010) Senior Secondary School Chemistry Practical Manual/Workbook EMC &CO Nig. ISBN:97835328-2-0

 

EXPERIENCES/Membership OF SOCIETIES

Post Doctoral Fellow April-2012- March 2013-National Institute of  Parasitic Diseases, Chinese

Centre for Disease Control, Shanghai, China.

 

Lecturer 1-October 2011-Date – Department of Medical Biochemistry, College of Medicine, University of Nigeria, Enugu Campus.

 

Lecturer 11- September, 2008 – September 2011  Department of Medical Biochemistry, College of Medicine, University of Nigeria, Enugu Campus.

 

Assistant Lecturer –February, 2007-September, 2008- Department of Medical Biochemistry, College of Medicine, University of Nigeria.

 

Secretary NUGA UNN HIV/AIDS Awareness Committee-2009

 

Coordinator Post Graduate Programs Medical Biochemistry Department University of Nigeria Enugu Campus 2010-2013.

 

Member Nigerian Society of Biochemistry and Molecular Biology 2008 – Date

 

Member British Biochemical Society 2008 – Date

 

Research Fellow Chinese Institute of Parasitic Diseases 2012- Date

 

Member Nigerian Red Cross Society 2011-Date.

 

TRAINING ATTENDED

  1. Participated in the research team on stigma and discrimination in Enugu State. 2008
  2. Gender mainstreaming and HIV/AIDS in the Hospital section. Organized by UNICEF in Enugu 2007.
  3. International Union of Biochemistry and molecular Biology in conjunction with EMBO, ICGEB and FEBS organized training on “cellular and molecular basis of infectious diseases” held in Hermanus, Cape Town South Africa. 27th February – 11 March 2008.

 

CONFERENCES

1.IUBMB Advanced Summer School Organised in Hermanus Cape Town, South Africa 29th March-10th April 2008

Changes in some biochemical parameters of Kidney and Liver functions of whistar rats co-administered with  Halofantrine and Garcinia Kola seed extract.

Ezeh, C. O. Ubenyi, S. M. Ogbunude, P. O. J. Nweke, M. Anyaechie,  B. U. Ibegbu, D. M. Eze, A.A. and Iyare, E.E.

2.Zoological Society of Nigeria 4th Annual Conference Organised at Owerri, Imo State Nigeria 20th-24th Nov. 2007

Trace metals in Yoghurt, ice-cream and fura da nunu sold in Owerri, Imo State Obiekezie, S. O. Eze, C. O. Okhiai, O. and Verla, A. W

3   The first Forum on Surveillance and Response System leading to Tropical Diseases  Elimination, Shanghai, China, 16-18th June, 2012

 

REFERENCES

  1. Prof. E. O. Anosike

Department of Biochemistry

Faculty of Science

University of Port Harcourt

Port Harcourt.

 

  1. Prof. P. O. J. Ogbunude

Medical Biochemistry Department

Faculty of Medical Sciences

College of Medicine

University of Nigeria

Enugu Campus.

 

  1. Prof. Hu Wei

National Institute of Parasitic Diseases

Chinese Centre for Disease Control

Shanghai, China.

 

 research line

Full Name: OKOJIE Akhabue Kenneth

Date of birth: 2nd May, 1983

Nationality: Nigerian

Permanent home address: Thelver Pharmacy, Opposite University of Benin Teaching Hospital,

Along Ugbowo-Lagos Road, Ugbowo, Benin City, Edo State.

Current postal address: Department of Physiology, University of Nigeria, Enugu Campus, Enugu, Enugu State, Nigeria.

Phone Number: +2348063762090

Email: pintos4live@yahoo.com

Marital status: Single

Institutions attended with dates/Academic/professional qualifications

2012-Till Date: University of Nigeria, Enugu Campus, PhD Physiology (in progress)

2008-2010: University of Benin, Benin City, MSc Physiology.

2002-2005: Ambrose Alli University, Ekpoma, BSc (Hons) Physiology.

Work experience with dates

  1. 2012- Till Date: Biostatistics/Physiology Lecturer, School of Post Basic Nursing, University of Benin Teaching Hospital, Benin City, Edo Sate, Nigeria.
  2. 2010-2012: Medical Representative, Ranbaxy Nigeria Limited.

Courses/Workshop Attended

  1. Neurobiology of Disease Workshop: Human Brain Disorders in a Dish: Induced Pluripotent Stem Cell Models of Disease. San Diego, CA, USA. 8th Nov, 2013.
  2. IBRO workshop on “writing skills” Rabat, Morocco. 9th-12th June, 2013.
  3. 1st IBRO School on Insect Neuroscience and Drosophila Neurogenetics. School of Health Sciences, Kampala International University, Ishaka, Uganda. 20th August-7th September, 2012.
  4. IBRO School on Basic and Clinical Neurosciences. Ibadan, Nigeria. 5-9th December, 2011.

Conference Attended

  1. Society for Neuroscience. Washington, DC, USA, 15th -19th November, 2014

 

  1. Society of Neuroscientist of Africa. Rabat, Morocco, 13th-17th June, 2013.

Poster Presentation: Effects of induced pain on spatial memory in male Sprague dawley rats.

 

  1. Society for Neuroscience. San Diego, CA, USA, 9th -13th November, 2013. Poster Presentation: Ethanol-induced antinociception in male albino rats: Role of adrenergic blockers.

 

  1. Society for Neuroscience International Fellows Poster Session. San Diego, CA, USA, 9th November, 2013. Poster Presentation: Relationship between the plasma testosterone level and pain reaction times in male rats.

 

Awards

  1. November 2013: SfN/IBRO Travel Grant. To attend Society for Neuroscience Annual Meeting 2013, San Diego, California, USA.

 

  1. February 2014 – March 2014: ISN-CAEN Research grant to visit Prof. J. Attems and Dr. G. Saretzki’s Lab, Institute for Ageing and Health, Newcastle University, Newcastle, UK.

 

Membership of Professional Organization

  1. Member, Society of Neuroscientists of Africa (SONA)
  2. Member, International Society for Neurochemistry (ISN)
  3. Graduate Member, Society for Neuroscience (SfN)

Publications

  1. K. Okojie and O. A. Oyekunle (2013): Depo-Provera effects on Wistar rat performance in the Y-maze. Metab Brain Dis. DOI 10.1007/s11011-013-9460-9.
  2. I. Ebomoyi and A.K. Okojie (2012): Physiological Mechanisms underlying the use of Garcinia kola Heckel in the treatment of asthma. ARJM 8 (1): 5-8.
  3. Oko-ose J, Okojie A.K, Iyawe V.I (2011): Physiological basis of pregnancy inducedhypertension. Journal of Medicine and Medical Science; 2(7): 939-945.
  4. AOyekunle, T.P Ogundeji and A.K. Okojie (2011): Behavioral modifications related toconsumption of a “soft” adaptogen, Bee Honey, by rats. Neurophysiology; 43 (1):46 – 50.
  5. AOyekunle, A.K. Okojie and U.S. Udoh (2010): Anagelsic and anti-inflammatory effects ofan extract of FadogiaAgrestis in rats. Neurophysiology; 42 (2):147 –151.
  6. AOyekunle, G.F Ibironke, S.F. Ige, U.S. Udoh and A.K. Okojie (2009): Relationshipbetween the plasma testosterone level and pain reaction times in male rats. Neurophysiology; 41(3):231 – 234.
  7. Udoh U S, Oyekunle O A, Ige S F, Okojie A K, Ogunwale E B (2009): Effect of oraladministration of aqueous kola nut extract (Kola nitida) on reproductive hormones in maleSprague dawley rats. Afr.J.MedSci; 2(2):31-34.
  8. Okojie A.K., Nwaokpara A.O. and Ute I (2008): Seasonal variation of blood pressure in firstpregnancies. J. Med. Pharm, Sci; 4 (1): 1 – 4.
  9. Okojie A.K., Dibie D.C and Inegbenebor U (2008): Pathophysiological implications of Obesity and its relationship with diabetes mellitus. J. Advan. Med. Pharm. Sci., 2(4): 16-18.

 

Service to Nation

2007-2008: National Youth Service Corp (NYSC), Technology Assistant, Department of Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.

Extra-curricular activities

Reading, Surfing, Football and Chess.

Names and addresses referees

Dr. E. Iyare

Department of Physiology

University of Nigeria

Enugu Campus

Enugu Sate. Nigeria.

eghosa.iyare@unn.edu.ng

 

Dr. G. Saretzki

Lecturer in Ageing Research

Institute for Ageing and Health

Campus for Ageing and Vitality

Edwardson Building

Newcastle upon Tyne, NE4 5PL, UK

+441912481214

gabriele.saretzki@ncl.ac.uk

 

Dr. Ute Inegbenebor

Department of Physiology

College of Medicine

Ambrose Alli University

Ekpoma, Edo State, Nigeria.

druteinegbenebor@yahoo.com

 

 

 

research line

 

PERSONAL DATA

Name:                                                              Morufu Eyitayo BALOGUN

Gender:                                                           Male

Date of Birth:                                                  June 1, 1976

Place of Birth:                                                 Iseyin, Oyo state

Marital Status:                                                 Married

Nationality:                                                     Nigerian

State of origin:                                                            Oyo

Local Government Area:                                Iseyin

Permanent Home Address:                            Alagbede Compds, Ago-Ijemba, Iseyin, Oyo State

Present contact Address:                                No. 2, Nwankwo Street, Abakaliki, Ebonyi state

Present Postal Address:                                  P.M.B 053, Physiology Dept., Ebonyi State University

E-Mail Address:                                              marufbalogun@yahoo.com

Phone Numbers:                                              +234-8104031671, +234-8037719726

 

EDUCATIONAL BACKGROUND

  1. Educational Institutions Attended (With Dates):

University of Nigeria, Nsukka, Enugu state                                             2013-Till date

University of Ibadan, Nigeria                                                                   2008 – 2010

University of Ilorin, Ilorin, Kwara State                                                  1997 – 2003

Iseyin District Grammar School, Iseyin, Oyo State                                 1989 – 1994

Koso Community Primary School, Iseyin, Oyo State                              1982 – 1988

  1. Academics and Professional Qualifications Obtained (With Dates):

PhD in Human Physiology (Nigeria)                                                       In-view

  1. Sc. in Human Physiology (Ibadan) 2010
  2. Sc (Hons.) in Human Physiology (Ilorin) 2003

West African Senior Secondary School Certificate                                 1994

Primary School Leaving Certificate                                                          1988

 

WORKING/ TEACHING EXPERIENCE (WITH DATES)

Anatomy & Physiology Tutor

School of Health Technology,

Port Harcourt, Rivers State                                                                       2003 – 2004

 

Biology Teacher

St, John’s Catholic Grammar School,

Iseyin, Oyo State                                                                                      2004 – 2005

 

Biology Teacher

Kelani College,

Iseyin, Oyo State                                                                                     2005 – 2008

 

Practical Demonstration to

200L Medical Students, University of Ibadan, Ibadan                           2008 – 2010

 

Part time Lecturer

School of Basic Midwifery,

Saki, Oyo State                                                                                         2009 – 2011

 

Assistant Lecturer

Department of Physiology,

College of Health Sciences,

Ebonyi State University, Abakaliki                                                         2011-2012

 

Lecturer II                                                                                              

Department of Physiology,

College of Health Sciences,

Ebonyi State University, Abakaliki                                                         2012-Till date

 

ACADEMIC PUBLICATIONS (WITH DATES)

Thesis / Dissertations

  • Is ethanol induced–ulceration affected by Chloroquine

administration in rats? (A Research Project Submitted to the

Department of Physiology, University of Ilorin)                                            2003

 

  • The effect of Aqueous and Methanolic Extracts of Persea

americana on Gastric Acid Secretion in rats. (A Dissertation

Submitted to the Department of Physiology, University of Ibadan)            2010

 

Research and Publications:

  1. Balogun M. E., Jeje S. O., Salami S. A., Onwe P. E. and Folawiyo M. A. (2015). Anti-ulcerogenic and gastric anti-secretory effects of Nauclea latifolia extract in male albino rats. J. Exp. Biol. 5 (2): 74-80.

 

  1. Balogun M. E., Nwachukwu D. C., Onwe P. E. and Folawiyo M. A. (2014). Gastric acid anti-secretory effect of aqueous leaf extract of Nauclea latifolia (Rubiaceae) in rats. Phytopharmcol.3 (6): 389-394.

 

  1. Balogun M. E., Folawiyo M. A., Besong E. E. and Jeje S. O. (2014). Effects of ethanolic fruit extract of Adenopus breviflorus (Lagenaria breviflora) on hematological indices in male albino rats. Physiol. Pharm. Adv. 4 (11): 501-508.

 

  1. Balogun M. E., Ajayi A. F., Oji O. J., Bessong E. E., Finbarrs-Bello E. and Folawiyo M. A. (2014). Toxicological and biochemical studies of ethanolic fruit extract of Adenopus breviflorus (Lagenaria breviflora Roberty) in male albino Wistar rats. J. Phytomed. Clin. Therap. 2 (9): 1112-1123.

 

  1. Oluwole F. S., Balogun M. E., and Adedeji G. T. (2013). Antisecretory effects of water melon (Citrullus lanatus) juice in male albino rats. Rev. Res. Biol. 3 (4): 358-366.

 

  1. Balogun M. E., Oji J. O., Besong E. E, and Umahi G. O. (2013). Evaluation of the antiulcer properties of aqueous leaf extract of Dialium guineense (Velvet Tamarind) on experimentally induced ulcer models in rats. J. Dev. Res. 3 (10): 106-110.

 

  1. Balogun M. E., Oji J. O., Besong E. E., Ajah A. A. and Michael E. E. (2013). Anti-ulcer activity of aqueous leaf extract of Nauclea latifolia (rubiaceae) on indomethacin- induced gastric ulcer in rats. J. Biotechnol. 12(32): 5080-5086.

 

  1. Oji J. O., Balogun M. E., and Besong E. E. (2012). Effect of Quarry dust on the lung function and leucocytes pattern in albino Wistar rats. Biomed. Sci. Afr. 10 (1&2): 40-42.

 

CONFERENCES/WORKSHOP ATTENDED (WITH DATES)

  1. 32 ND Annual Scientific Conference of Physiological Society of Nigeria (PSN), 22-24th August, 2012, University of Calabar, Nigeria

 

  1. Grantsmanship Training Workshop, 11-12th February, 2014, Organized by Directorate of Research, Innovation & Commercialization (EBSU–DRIC), Ebonyi State University, Nigeria.

 

  1. Statistical Analysis of Data Training Workshop, 5-7th August, 2014, Organized by Directorate of Research, Innovation & Commercialization (EBSU–DRIC), Ebonyi State University, Nigeria.

 

  1. Quality Assurance Workshop/Training, Organized by National Universities Commission (NUC), 8-9th October, 2014, Ebonyi State University, Nigeria.

 

  1. TETFund Proposal Development Training Workshop, 23rd March, 2015, Organized by Directorate of Research, Innovation & Commercialization (EBSU–DRIC), Ebonyi State University, Nigeria.

 

 

STUDENTS SUPERVISION

  1. Anti-ulcer activity of aqueous leaf extract of Nauclea latifolia (rubiaceae) on indomethacin- induced gastric ulcer in rats. B.Sc. Project by Michael Emeka Michael, Department of Anatomy, Faculty of Basic Medical Sciences, Ebonyi State University, Abakaliki, Nigeria (2011/2012 session).
  2. Evaluation of the antiulcer properties of aqueous leaf extract of Dialium guineense (Velvet Tamarind) on experimentally induced ulcer models in rats. B.Sc. Project by Anikputa Daniel Chimdindu, Department of Anatomy, Faculty of Basic Medical Sciences, Ebonyi State University, Abakaliki, Nigeria (2012/2013 session).
  3. Effect of Quarry dust on the lung function and leucocytes pattern in albino Wistar rats.       B.Sc. Project by Igwe Chidiebere, Department of Anatomy, Faculty of Medicine, Ebonyi State University, Abakaliki, Nigeria (2012/2013 session).
  4. Toxicological and biochemical studies of ethanolic fruit extract of Adenopus breviflorus (Lagenaria breviflora Roberty) in male albino Wistar rats. B.Sc. Project by Omabe Paul Chioma, Department of Anatomy, Faculty of Medicine, Ebonyi State University, Abakaliki, Nigeria (2013/2014 session).
  5. Effect of ethanolic fruit extract of Adenopus breviflorus (Lagenaria breviflora Roberty) on hematological parameters in male albino Wistar rats. B.Sc. Project by Anthony Paul Okoro, Department of Anatomy, Faculty of Medicine, Ebonyi State University, Abakaliki, Nigeria (2013/2014 session).
  6. Anti-ulcerogenic and gastric anti-secretory effects of Nauclea latifolia extract in male albino rats. B.Sc. Project by Nwachukwu Nancy Gift, Department of Anatomy, Faculty of Medicine, Ebonyi State University, Abakaliki, Nigeria (2014/2015 session).

 

CURRENT RESEARCH ACTIVITIES

  • The main focus of my research activities is on the likely potency of herbal preparations äs a basis for anti-ulcer medication, and possible development of proto-type anti-ulcer drugs from herbal Also, dietary regimen in the prevention and amelioration of peptic ulceration. I hope to generate emperical data that can be subjected to clinical trials which will help in regulation and formulation of policies on incorporation of traditional medicine into Health Care delivery of my country.

 

DETAILS OF ADMINISTRATIVE EXPERIENCE

  • Academic Course Adviser for 200L & 300L Medical Students, Faculty of Medicine, College of Health Sciences, Ebonyi State University, Abakaliki, Ebonyi State for (2012/2013) academic session.
  • Academic Course Adviser for 400L Anatomy Students, Faculty of Medicine, College of Health Sciences, Ebonyi State University, Abakaliki, Ebonyi State for (2013/2014) academic session.
  • Academic Course Adviser for 100L Medical Students, Faculty of Medicine, College of Health Sciences, Ebonyi State University, Abakaliki, Ebonyi State for (2014/2015) academic session.

PRESENT JOB STATUS

  • Lecturer II, Department of Physiology, Faculty of Medicine, College of Health Sciences, Ebonyi State University, Abakaliki, Ebonyi State.

SKILLS AND ABILITIES

  • Strong Fluent English written, oral, and presentation communication abilities
  • Analytical and critical thinking skills
  • Computer literacy

 

SERVICE TO THE COMMUNITY

Rectitude Society, Iseyin branch (Social Secretary)

  • Organizing career talk in public and private secondary schools
  • Enlightment programme on AIDS control and prevention
  • Enlightened general public on sensitive societal issues such as Immunization

 

MEMBERSHIP OF THE PROFESSIONAL BODIES

  • Physiological Society of Nigeria ( Member)
  • Africa Physiological Society ( Member)

 

EXTRA CURRICULAR ACTIVITIES

Tennis, Traveling and Reading

 

REFERENCES

  1. Professor Y. Raji

Department of Physiology,

Faculty of Basic Medical Sciences,

College of Medicine,

University of Ibadan, Nigeria.

yoraji@yahoo.com, +234-8023263626

 

  1. Professor A. O. Afoke

Head, Department of Physiology,

Faculty of Medicine,

College of Health Sciences,

Ebonyi State University, Nigeria.

okoroafoke@yahoo.com, +234-8063918611

 

  1. Dr D. C. Nwachukwu, Senior Lecturer,

Department of Physiology,

Faculty of Medical Sciences,

College of Medicine,

University of Nigeria, Enugu Campus, Nigeria

danynwachukwu@yahoo.com, +234-8037245474

 

research line

 

IGBERAESE CORDILIA OMUEKPEN

321,Borehole Road, Ekpoma, Edo State.

Email: cordie2age@gmail.com

Tel: 08131232377, 08055513314

 

 

PERSONAL DATA:

Date of Birth:              8th December, 1988

Sex:                              Female

Marital Status:             Single

State of Origin:           Edo State

Local Govt. Area:       Esan Central

Nationality:                 Nigeria

EDUCATION:

University Of Nigeria Enugu                                                              in view

M.Sc Medical Physiology

Ambrose Alli University, Ekpoma                                                                   2006-2011

B.Sc Medical Physiology (Second Class Upper Division)

Ambrose Alli University, Ekpoma                                                                  1999-2005

(S.S.C.E)

Blessing Primary School, Ekpoma                                                                  1995-1999

(F.S.L.C)

 

WORK EXPERIENCE:

Editor,Annals of Health Sciences Research journal                                                 2014-date

Editor, Journal of Basic and Clinical Reproductive Sciences                                   2014-date

Enugu State University College of Medicine                                                 2011-2012

(NYSC)

 

Volunteer Work:

Community Development Service                                                                             2012

(Donation of Projectors to Enugu State College of Medicine)

 

REFEREES:

  1. Dr. Ute Inegbenebor

Dean FBMS,AAU,

Ekpoma, Edo State

+2348065278467

  1. Prof. Uchenna I. Nwagha

Dean,FMS, UNEC,

Enugu State

+2348033128233

  1. Dr. Eghosa E. Iyare

Physiology department,UNEC,

Enugu State

+2348052820041