NATURAL PRODUCTS RESERCH GROUP

NATURAL PRODUCTS RESERCH GROUP
BASED IN THE DEPARTMENT OF PHARMACOLOGY AND TOXICOLOGY
UNIVERSITY OF NIGERIA, NSUKKA

1. NAME: NATURAL PRODUCTS RESEARCH GROUP (NAPREG)

2. RESEARCH GROUP LEADER: Professor Peter A. Akah

3. MEMBERS:

i. Dr. T. C. Okoye
ii. Dr. A. C. Ezike
iii. Dr. C. S. Nworu
iv. Pharm C. A. Onyeto
v. Pharm. F. N. Mbaoji
vi. Pharm. I. F. Nwabunike

4. OBJECTIVES

• The development of drugs from natural products.

• To screen medicinal plants and other natural products for posssible pharmacological activity

• To fractionate, isolate and characterize plant secondary metabolites responsible for pharmacological effects or activity.

• To chemically produce lead compounds for new drug molecule.

• To develop new drugs that will be effective as antiinfectives, antimalarials, antidiabetics, antiepileptics, analgesics and immune stimulation.

• To institute a functional collaboration and Exchange Research Programmes with some renowned foreign Pharmacology and Toxicology Schools and Research Centers in the developed nations

• To attain the status of a “Centre of Excellence in Pharmacology Research” in Nigeria. A Department that will be a reference point for other Pharmacology Departments in the country.

• To increase research activities and publications emanating from the Department. This invariably will increase the visibility of the University during the web-metric rankings.

5. ON-GOING RESEARCH
 Many medicinal plants have so far been tested for activity which scientifically has supported the ethnomedicinal claim.

 We have isolated compounds with antiidiabetic, immunomodulatory and anticonvulsant effects. The compound will be subjected to possible pre-clinical testing.

 Other plants are presently being studied.

6. ACTION PLAN
• To establish a standard Natural Products Laboratory for Drug Research and Development from Medicinal Plants for undergraduate and Post-graduate students

• To establish a functional Cell Culture Laboratory for in vitro assays of drugs and putative drug materials and natural extracts. This research facility is to facilitate research in modern drug treatments using high throughput assays of putative drug materials.