Prof. Okoro Uchechukwu Chris.

Department: Pure And Industrial Chemistry
Faculty: Physical Sciences
Designation : Professor
Email: uchechukwu.okoro@unn.edu.ng
Phone: : +2348038995403; +2347059643502; +2347081474361


Publications (Articles and Journals):

Journal Articles/Books/Scientific Presentations/Industrial R&D Innovations

  1. U C Okoro and C O Okafor, A new Synthesis of ‘Three Branched’ Diazaphenothiazine Dyes, Dyes and Pigments 9, 427(1988).
  2. U C Okoro, Synthesis of New Triaza and Tetraaza Analogues of phenothiazine, Indian J. Chem. 29B, 177 (1990).
  3. U C Okoro and C O Okafor, An Unequivocal Synthesis of benzo[a][1,4]benzoxazino[3,2-] phenoxazine, Journal of the Nigeria Academy of Science 2, 77 (1990).
  4. U C Okoro, Synthesis of New ‘branched’ benzoxazinophenothiazine Ring System, Indian J Chem. 30B, 18 (1991)
  5. U C Okoro, The First Aza-analogues of Dibezotriphenodithiazine Ring System, Indian Journal of Chemistry 30B, 22(1991).
  6. U C Okoro and C O Okafor, New Non-Linear Polycyclic Azaphenothiazine Dyestuffs, Dyes and Pigments 16, 149 (1991).
  7. U C Okoro Pigments Used in Paints, Proceedings of CSN Enugu State Chapter Workshop on the Science and Technology of Paints, 1, 42 (1992).
  8. U C Okoro, J U Oguakwa, C A Nwadinigwe, F A Onwodi & F I Nwabue, Principles of Inorganic Chemistry …...The Fundamental Aspects. The Academic Publishers, Nsukka , 1997
  9. U C Okoro, S O Onyiriuka, C A Nwadinigwe, M N Nwaji & L E S Akpanisi, Principles of Organic Chemistry….. The Fundamental Aspects, The Academic Publishers, Nsukka, 1997.
  10. U C Okoro, Solutions to Problems in Basic Organic Chemistry……. With Notes, Academic Publishers Nig. Ltd, Nsukka, 1999.
  11. U C Okoro, P A Obuasi, M J Kelleher & J I Ume, Basic Principles of Physical Chemistry, John Best Publishers Nig. Ltd, Enugu, 2001
  12. U C Okoro, Intermidiate Organic Chemistry Vol. One, Academic Publishers Nigeria Ltd, Nsukka, 2003.
  13. U C Okoro, Manual of Basic Organic Chemistry Praticals, Academic Publishers Nig Ltd, Nsukka, 2004.
  14. U C OKoro B E Ezema, Synthesis of New Non- Linear Diazaphenothiazine Ring System, International Journal of Chemistry, 16(3) (2006).
  15. U C Okoro and A O Ijeoma, Synthesis of New Non-Linear Polycyclic DiazaphenothiazizneRing System, International Journal of Chemistry, 16(4) (2006).
  16. U C Okoro and A U Ofoefule, Synthesis of Some New Aryl Derivatives of 1, 11- Diaza-5H- benzo[a]phnothiazin-5-one, International Journal of Chemistry, 18(3), 109 (2008)
  17. U C Okoro and F Okpunor and R O Ugwoke, The First ‘Angular’ Triazaphenoxazine and the Related Diaza- Analogues and Derivatives by Metal Catalyzed Coupling Reactions, International Journal of Chemistry, 19(3), 107 (2008)
  18. U C Okoro, M A N Nnabugwu and C A Nwadinigwe, Synthesis of Some New ‘Angular’ Diazaphenothiazine and their Anilino Derivatives as Stable Cyclic Quinoneimines, International Journal of Chemistry 18(4), 171(2008)
  19. U C Okoro, E A Onoabedje and E M Odin, The First ‘Angular’ Triazaphenothiazinone, the Related Diaza-Analogue and their Anilino Derivatives, International Journal of Chemistry, 19(4), 197 (2009)
  20. U C Okoro, U I Onwuachu and F Musa, Palladium Catalysed Regioselective Synthesis of Some Anilino Derivatives of Angular Diazaphenothiazinone and the Related Diaza Analogue, International Journal of Chemistry, 19(3), 208 (2009)
  21. U. C. Okoro , E. U. Godwin-Nwakwasi, S O Onyiriuka, Synthesis of Novel Allylic N- alkylated Anilines Using Phosphate Esters and Crotyl Chloride, African J, Bio. Sci. 3(1), 33 (2010).
  22. M. A. Nnabugwu and U, C Okoro, New Dyes for Petroleum Products, J. Emerging Trends in Engr. and Appl. Scis , 3(1), 8-11 (2011)
  23. U C Okoro, A Utime and M N Nnabugwu, Synthesis of Functionalized Triphenodioxazines via Palladium Catalyzed Cross-Coupling Reacstions, International J. Chem, 21(3), 20 (2011).
  24. U C Okoro, M A Nnabugwu, C A Nwadinigwe and L E S Akpanisi, Synthesis of 1,9,10-triaza-5H-benzo[a]phenothiazin-5-one Derivatives, Intl. J. Chem. 21(3), 201(2011).
  25. U C Okoro, Principles of Organic Chemistry…the Fundamental Aspects, 2nd Edition, Academic Publishers, Nsukka, 2012.
  26. A U Ofoefule, U C Okoro and O D Onukwuli, Biogas Production from Waste By-product of Ethanol Production: 1. Digestion of Pure Waste, Int. J. Current Res, 4(11), 82-85, (2012).
  27. A U Ofoefule, U C Okoro and O D Onukwuli, Biogas Production from Waste By-product of Ethanol Production: 2, Effect of Batch co-digestion with Some Animal and Plant Wastes on Biogas Production, Int. J. Current Res, 4(11), 86-91, (2012)
  28. A U Ofoefule, U C Okoro, C N Ibeto and OD Onukwuli, Biodiesel Production from Tigernut (Cypenis esculartus) oil and Characterization of its Blend with Petro-diesel, Physical Review and Research Intl. 3(2), 145-153, (2013)
  29. A U Ofoefule, U C Okoro , O D Onukwuli and C. N. Anyanwu, Biogas Production from Waste By-product of Ethanol Production: 3, Modeling of Gas Yield with Time, Physical Review and Research Intl. 3 (1), 18-27. (2013).
  30. U C Okoro and A D Jacob Copper-Catalyzed Arylation Reaction in the Synthesis New Derivatives of Angular Triazaphenoxazinone, J. Chemistry and Materials Research, 6(9), 37-40 (2014).
  31. D. I Ugwu, and U. C Okoro, Synthesis, Characterisation and Antifungal activities of [4- methylphenyl sulphonamide]-N-(pyridin-2-yl)acetamide derivatives, Medicinal Chemistry, 4, 330-333 (2014).
  32. C.F. Ozoh, U.C Okoro, and D.I Ugwu, (2014) Synthesis and Antimicrobial activities of N-(heteroaryl substituted)-p-toluene sulphonamides, Organic Chemistry International, 2014, doi:10.1155/2014/748257
  33. D. I Ugwu and U. C. Okoro Synthesis, (2014) Characterisation and Evaluation for Antibacterial Activities of N-Pyridin-2-yl Substituted-p- Toluene Sulphonamoyl Ethanamides, Int. J. Sci. Res. 3(9), 35-38.
  34. D.I. Ugwu, U .C Okoro., T.D. Chukwurah (2014).Nickel Catalyzed Synthesis of N-aryl and N-heteroaryl Substituted Benzene Sulphonamides and their Biological Activity Evaluation. Med Chem. 4:357-360,
  35. C. N. Igwe and U. C. Okoro, ( 2014) Synthesis, Characterization and Evaluation for Antimicrobial and Antifungal Activities of N-Heteroaryl Substituted Benzene Sulphonamides, Org. Chem. International, doi.org/10.1155/2014/419518
  36. S. A. Egu, U. C. Okoro and T. Wirth, Science open Research, 2015, (doi:10.14293/S2199-1006.1.SOR-CHEM.AALL9P.v1)
  37. MC Egbujor, UC, Okoro and DI Ugwu, Synthesis of New Derivatives of 1- Azaphenothiazine via Buchwald-Hartwig Amination methodology, Asian Journal of Chemistry, 27(4), 1469-1472, (2015).
  38. U .C. Okoro, C. N. Igwe, S. I. Egba, N.E. Nwankwo and E. G. Anaduaka (2015), The Activity of Synthesized N-heteroaryl Substituted Benzene Sulghonamides on the Liver and Kidney Marker Enzymes of Plasmodium berghei Infected Mice, J. Pharm.Chem. Biol Sci 3(1) 6-16
  39. E. L. Ayuk, S. U. Ilo, A. N. Njokunwogbu, G. A. Engwa, T. O. Oni and U. C. Okoro (2015), Synthesis and Characterization of 6-(4-Bromophenyl)-10- methyl-11-azabanzo[a]phenothiazin-5-one, Int. J. Materials and Chemistry,5(2), 44-47, doi:10.5923/j.ijmc.20150502.03.
  40. F. U. Eze and U. C. Okoro,(2015) Synthesis of Monoazaphenoxazine Derivatives via Buchwald-Hartwig Tandem Amination Protocol, Asian J. Chem., 27(12), 4401-4404.
  41. T. O. Oni, U. C. Okoro and D. I. Ugwu,(2015), Synthesis of 1- azabenzo[a]phenoxazin-5-one and 11-amino-1,8,10- triazabenzo[a]phenoxazin-5-one and their Functionalized Aryl Derivatives via Mizoroki-Heck Arylation Methodology, Oriental J. Chem., 31(1),371- 378.
  42. Ofoefule A.U., Okoro, U.C and Onukwuli O.D. (2015). Effect of hydrolysis reaction time on the reducing sugar yield of Acha (Digitaria exilis) and Finger millet (Eleusine coracana) starch for bioethanol production. Chem. Sci. Trans 4 (2), 331-336 , DOI:10.7598/cst2015.986
  43. W. Igori, V. E. Okposhi, B. C. Obi and U. C. Okoro (5015), Synthesis and Characterization of Zinc Oxide (ZnO) Nanowire, Nanomedicine and Nanotechnology, dx.doi.org/10.4172/2157-7439.1000321.
  44. Odaa, ME, Okoro, UC, Ugwu, DI (2015) Synthesis of Novel Angular Diazaphenoxazinone Derivatives via Palladium Catalyzed Buchwald-Hartwig Amidation Protocols, Asian Journal of Chemistry, 27(8), 3069-3073
  45. Ugwu, DI, Okoro, UC, Ezema, BE, Eze, FU, Ekoh, OC, Egbujor, MC, Ugwuja, DI. (2015) Syntheses and Pharmacological Applications of Chalcones : A Review, Int. J. Chem. Sci.: 13(1), 459-500
  46. Edoka, OL, Okoro, UC, Ugwu, DI (2015) Synthesis of New Derivatives of 1,9- Diazaphenoxazine Carboxamide Derivatives via Buchwald-Hartwig Amidation Protocol, Asian Journal of Chemistry, 27(9), 3463-3467.
  47. F. A. Lateef, O. D. Onukwuli, U. C. Okoro, P. M. Ejikeme, and P. Jere, (2014), Some Physical Properties and Oxidative Stability of Biodiesel Produced from Oil Seed Crops, Korean J. Chem., 31(5), 725-731.
  48. N.J.N. Nnaji, J.U. Ani, L.E. Aneke O.D. Onukwuli, U.C. Okoro and J.I. Ume (2014), Modelling the Coag-Flocculation Kinetics of Cashew nut Testa Tannins in an Industrial Effluent, J. of Industrial and Engineering Chem., 20, 1920-1935.
  49. M.N. Orjioke, U.C. Okoro, C.N. Igwe, A.N. Udeh (2015), Synthesis and Characterization of Zeolite and its Application in Adsorption of Nickel from Aqueous Solution, J. of Pharmaceutical, Chemical and Biological Sciences, 3(4), 592-600.
  50. U C Okoro , J. Ayogu and E. Ojarikre, (2016), Synthesis of New Hetero- Phenylamino Derivatives of Benzo[a]phenoxazin-5-one via Palladium- catalized Buchwald-Hartwig Amination Protocol. JUKULL Journal, 66(4), 131- 140.
  51. U C Okoro, M. A Ezeokonkwo, E A Ujah and R C Nweloke, (2016), Synthesis of Highly Functionalized Angular Azaphenoxazines and related Benzo Analogues via Suzuki-Miyaura Cross-coupling Reaction,Asian J. Chem. 28(2), 317-324.
  52. U C Okoro , and E L Ayuk, A. N. Njoku nwogbu, S. U. Ilo, G. A. Engwa and T. O. Oni (2015), Tandem Catalysis of New Aza Angular Phenothiazine Ring System, American J. Org. Chem. 5(2), 78-81
  53. U C Okoro, A. E. Onoabedje and D.W. Knight, A. Sarka (2015), Functionalization of phenothiazine and phenoxazine ring systems via Suzuki Miyaura Cross-Coupling Reactions, J. Het. Chem.,doi: 10.1002/jhet2485.
  54. E.A Onoabedje, U. C. Okoro, D. W. Knight, and A. Sarka (2016), Synthesis and Structure of New Alkynyl Derivatives of Phenothiazine and Phenoxazine, J. Sulfur Chem., dx.doi.org/10.1080/17415993.2015.1131827.
  55. U C Okoro, and A.D. Jacob (2014), Copper- catalyzed Arylation Reaction in the Synthesis of New Derivatives of Angular Phenoxazine, Chem and Materials Research, 6(9), 37-40.
  56. A.I. Ihejieto, U.C. Okoro and A.D. Jacob (2015), Copper Catalyzed N- Arylation of Angular Triazaphenothiazine, Chem and Materials Research, 7(4), 144-146.
  57. A U Ofoefule, U C Okoro and O D Onukwuli, 2016), Modeling of gelatinization time against water content for some starch feedstock for bioethanol production, Chem. Sci. Trans. 5(1), 35-40.
  58. A U Ofoefule, U C Okoro and O D Onukwuli,(2015), Effect of Hydrolysis reaction time on the reducing sugar yield of Acha (Digitaria exilis) and Finger millet (Eleusine coracanna) starch for bioethanol production, Chem. Sci. Trans, (2016), 4(2), 331-336.
  59. Ofoefule A.U., Okoro, U.C and Onukwuli O.D. (2015). Effect of hydrolysis reaction time on the reducing sugar yield of Tacca (Tacca involucrata) and Tigernut (Cyperus esculentus) starch. Der Pharma Chemica. 7(6), 324-329.
  60. C. B C. Ikpa and U. C. Okoro (2016), Synthesis of New Paratoluene Sulphonamide Derivatives of Amino Acids and their Antibacterial Activities, IOSR J. Appl Chem. 9(6), 31-34.
  61. S. A. Egu, U. C. Okoro and E. A. Onoabedje,(2016), New Aryl Derivatives of Quinolinequinone and Related Heterocyclic Compounds, J. Het. Chem., DOI:10.1002/jhet.2745.
  62. J. I Ayogu, U. H. Okei and U. C. Okoro, (2016), Synthesis of Functionalized Aryl Derivatives of 1,11-Diazabenzo[a]phenoxazin-5-one and 1- Azadibenzo[a,j]phenoxazin-5-one via Pd-Catalyzed Mizoroki-Herk Reaction, Int. J. Scientific Res., 5(7), 2277-8179.
  63. E. I. Ayuk, U. C. Okoro and M. O. Ugwu, (2016), A Review on Biological atalysts in Organic Synthesis, Int. J. Adv. Engr. Res and Appl., 2(6) 296-321.
  64. D. Ugwuja and U. C. Okoro, (2016), Computer Aided Drug Discovery - Structure and Ligand Based Design, FUW Trends in Scie and Tech J. 1(1), 158-164.
  65. E. A. Onoabedje, A. Ibezim, S. N. Okafor, U. S. Onoabedje and U. C. Okoro , (2016) Oxazin-5-one as a New Class of Penicillin Binding Protein Inhibitors: Design, Synthesis and Structure Activity Relationship, Plos-one, DOI:10.1371/journal.pone.0163467.
  66. C. B. C Ikpa, U. C. Okoro, C. I. Ubochi and K. O. Nwanorh, (2016), Synthesis, Characterization and Antimicrobial Activity of 2-Phenylsulphonamide Derivatives of Some Amino Acids, Intl. Letters of Chem., Phy and Astro, 70, 2299-3843.
  67. C.B.C Ikpa, U. C. Okoro, C. Ubochi, K. O. Nwanorh and S. O. Onoja (2016), Preliminary Screening for Anti-inflammatory, Anti-Nociceptive and Antioxidant Activities of Five New Synthesized Paratoluene Sulphonamide Derivatives of Amino Acids, Int. J. Pharmacology and Ethnomedicine, 5, 74- 78.
  68. E. U. Godwin-Nwakwasi, U C Okoro, A. O. Ijeoma and M. A. Ezeokonkwo (2017), Palladium Catalyzed Transformation and Antimicrobial Screening of Novel Angular Azaphenothiazines, Asian J. Chem., 29, 742-748.
  69. D. I. Ugwu, U. C. Okoro, P. O. Ukoha, S. Okafor, A. Ibezim, N. M. Kumar,(2017) 'Synthesis, Characterization, Molecular Docking and in vitro Antimalerial Properties of New Carboxamide bearing Sulphonamide' European J. Med, Chem. 135, 349-369.
  70. D. U. Ugwu, U. C. Okoro, H. Ahmad,(2017) 'New Carboxamide Derivatives Bearing Benzenesulphonamide as selective COX-II Inhibitor' PLos ONE 12(9) DOI.org/10.1371/journal.pone.0183807.
  71. D. I. Ugwu, U. C. Okoro and N. K. Mishra (2017) Synthesis, Characterization and Anthelmintic Activity Evaluation of Pyrimidine Derivatives Bearing Carboxamide and Sulphonamide Moieties, J. Serbian Chem Soc. 82 in press
  72. S. A. Egu, A. Ibezim, A. E. Onoabedje and U. C. Okoro (2017), Biological and In Silico Evaluation of Quinolinedione and Naphthoquinone Derivatives as Potent Antibacterial Agents, Medicinal and Drug Discovery, DOI: 10.1002/slct.201700692.
  73. M. A. Ezeokonkwo, O. N. Ogbonna, S. N. Okafor, E. U. Godwin-Nwakwasi, F. N. Ibeanu and U. C. Okoro (2017), Angular Phenoxazine Ethers as Potent Multi-microbial Tagets Inhibitors: Design, Synthesis and Molecular Docking Studies, Front. Chem., doi.org/10.3389/fchem.2017.00107.
  74. D. I. Ugwu, U. C. Okoro and D. I. Ugwuja (2018), Synthesis, Antibacterial, Antifungal and Antioxidant Activities of N-pyridin-3-yl Substituted[phenylsulphonamido] Acetamide Derivatives, Pakistan Journal of Pharm. Scis, 31(4) in press http://www.pips.pk/?page_id=282
  75. S. A. Agbo, V. A. Anoh and U. C. Okoro (2014), Nickel Catalyzed Amidation Reaction in the Synthesis of Azaphenoxazine Carboxamides, J. Applicable Chem. 3(6), 2526-2532.
  76. D. I. Ugwu, U. C. Okoro, P. O. Ukoha, S. Okafor and A. Gupta (2018), Novel anti-inflammatory and analgesic agents: Synthesis, molecular docking and in vivo studies, Journal of Enzyme Inhibition and Medicinal Chemistry, 33(1), 405-415.
  77. D. I. Ugwu, U. C. Okoro and K. K. Mishra (2018), Synthesis, characterization and In Vitro antitrypanosomal activities of new carboxamides bearing quinoline moity, PLOS ONE, 13(1), e0191234.
  78. F. N. Ibeanu, E. A. Onoabedje, A. Ibezim and U. C. Okoro (2018), Synthesis, Characterization, computational and biological study of novel azabenzo[a]phenothiazine and azabenzo[b]phenoxazine heterocycles as potential antibiotic agent, Medicinal Chemistry Research, 27(4), pp 1093- 1102.
  79. D. I. Ugwu, U. C. Okoro and N. K. Mishra (2018), Synthesis of Proline derived Benzenesulfonamides: A Potenrt Anti-Trypanosoma bruceigambiense Agent, European J. Med. Chem. 154, 110-116.
  80. D. I. Ugwu, U. C. Okoro, N. K. Mishra and S. N. Okafor, (2018), Novel Phenoxazinones as potent agonist of PPAR-α: design, synthesis, molecular docking and in vivo studies, Lipids in Health and Disease, 17:120, DOI.org/10.1186/s12944-0764-y



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