Department of Medical Microbiology was founded as a component of Faculty of Medicine of the Medical School, University of Nigeria Enugu Campus (UNEC).  The Faculty was established in 1967.  the department is a major part of the division of Pathology Sciences of the former Faculty of Medical Sciences & Dentistry, now Faculty of Medical Sciences.

The Department of Medical Microbiology took off in earnest immediately after the civil war.  The department administratively operates as a single unit with two components the teaching wing in the College of Medicine and the diagnostic wing under University of Nigeria Teaching Hospital (UNTH).

Department of Medical Microbiology is involved primarily in teaching, research and laboratory diagnosis. The department teaches 3^rd MB;BS Medical Students Medical Microbiology.  However, some of the lecturers are also involved in teaching and supervising students from the School of Medical Lab. Sciences, UNTH, B.Sc. Medical Lab. Sciences, Faculty of Health Sciences & Technology (FHST), Medical Residents in our department, Medical residents in Community Medicine and B.Sc. Nursing Students.