The thermodynamic parameters of the adsorption of iodine, acetyl-salicylic acid [aspirin] sodium salicylate and pyridoxine hydrochloride onto the powder of sclerotium of pleurotus tuber-regium has been studied. Negative delta G values were obtained for the adsorption of the drugs onto the powdered sclerotium. The negative delta G values show that adsorption is favoured in this spontaneous process, that is, the process led to a decrease in the free energy of the system. The free energy of segregation or surface enrichment factor caused by combination of the material was 46. delta H values calculated for the adsorption of the drugs onto the sclerotium were all negative as well as the delta S values. All these indicate that the adsorption was an exothermic process.
Bollettino chimico farmaceutico 06/1998; 137(5):165-8.