The association characteristics of isotropic solutions of disodium cromoglycate in water and aqueous electrolyte solutions have been examined using light-scattering techniques. The association in these solutions may be satisfactorily described using anti-cooperative stepwise association models in which successive association constants decrease with increasing aggregate size. Size distribution curves show that the extent of association is limited mainly to dimers and trimers.
International Journal of Pharmaceutics 11/1984; 22(1):25-30. DOI:10.1016/0378-5173(84)90042-5