Two groups of broiler chickens were infected with infectious bursal disease virus (IBDV) and Aspergillus flavus or A. flavus alone, respectively. Loss in weight was 2.5 times more severe in the IBDV + A flavus birds than in those infected with A. flavus alone. Mottling of liver with grey spots was observed only in the IBDV + A. flavus broilers. Histopathological sections of the lungs showed more necrosis, granulomas and fibrosis in the IBDV + A. flavus group, and the fungus was reisolated for a longer period from this group than from birds infected with A. flavus alone. These observations indicate that IBDV infection can increase the severity of A. flavus aspergillosis.
Avian Pathology 04/1991; 20(1):167-71. DOI:10.1080/03079459108418751